Erythromycin (When ATH J01FA01)

When ATH:
J01FA01

Characteristic.

A white crystalline powder, odorless, bitter taste. It is soluble in water, well - alcohol. Hygroscopic.

Pharmacological action.
Antibacterial.

Application.

Infections of upper and lower respiratory tract, SARS, purulent-inflammatory diseases of the skin and its appendages, Diphtheria, erythrasma, gonorrhea, syphilis, Listeriosis, Legionnaires' disease, prevention and treatment of rheumatism intolerant of beta-lactam antibiotics; Ophthalmic ointment-conjunctivitis, .Aloe, trachoma.

Contraindications.

Hypersensitivity, liver disease, pregnancy, lactation.

Side effects.

Diarrhoeal disorders (nausea, vomiting, abdominal pain, and others.), abnormal liver function, generalized seizures, hallucinations, disturbances of consciousness, dizziness, reversible hearing loss, ventricular tachycardia, QT prolongation.

Cooperation.

Potentiates the effects and toxicity of antihistamines, ergot alkaloids, theophylline and benzodiazepines, digoksina, antykoahulyantov type of indirect action, karʙamazepina, cyclosporine, geksoʙarʙitala, phenytoin, dizopiramida, lovastatin and bromocriptine.

Overdose.

Symptoms: abnormal liver function, up to acute liver failure, and hearing loss.

Treatment: gastric lavage, diurez, gemo- E pyeritonyealinyi dialysis. Produced constant monitoring of vital functions (ECG, electrolyte composition of blood).

Dosing and Administration.

Inside, for 1.5-2 hours before delivery; adult: 250-500 mg 4 once a day; The highest single dose 500 mg, daily - 2 g; children: from 1 Year to 3 years - 400 mg / day, from 3 to 6 years is 500-750 mg/day, from 6 to 8 years - 750 mg / day, from 8 to 12 years — to 1 g / day, dividing by 4 admission.

B / introduce adults and children at the rate of 15-20 mg/kg/day as a continuous or intermittent infusion. In severe cases it is possible to use higher dosage is 4 g / day. Outwardly, 2 times a day lubricated solution affected skin, ointment applied to the affected area, in diseases of the eye for a lower or upper eyelid 3-5 times a day.

Precautions.

The use of erythromycin, comprising a benzene, for / in the injection is sometimes accompanied by the development of a fatal gasping syndrome in children, as well as acute hepatitis drug in adults and children.

Cooperation