Tinidazol

When ATH:
J01XD02

Pharmacological action.
Protivoprotozoynymi, antimicrobial.

Application.

Acute and chronic trichomoniasis, amebiasis and giardiasis, juccuya, anaerobic and mixed infections of various localization (lung abscess, of the brain, infective endocarditis, and others.).

Contraindications.

Hypersensitivity, blood disease, CNS disease in active phase, pregnancy (I trimester).

Restrictions apply.

Lactation (should stop breastfeeding), Age to 12 years (especially in case of violation of renal excretory function).

Side effects.

Diarrhoeal disorders (decreased appetite, nausea, sometimes vomiting, diarrhea), transient leukopenia; in the long-term use-Vertigo, lokomotornaya ataxia, dysarthria, sometimes cramps, paresthesia; in rare cases, allergic reactions.

Cooperation.

Compatible with antibiotics and sulfonamides (aminoglikozidy, Erythromycin, rifampicin, cephalosporins); not recommended for use with ethionamide. Phenobarbital accelerates inactivation in the liver. Proximity effect anticoagulants (to reduce the risk of bleeding is recommended to reduce the dose to 50%).

Dosing and Administration.

Inside, in Trichomoniasis and diloxanide once — 2 g during or after a meal; amebiase adults- 2 g 1 once a day for 2-3 days. Children of 0.05-0.06 g/kg 1 once a day for 3 days; When amebnom abscesse liver adult-4.5-10 Mr. full course, children - 0,05 g/kg for 5 days.

Cautions.

Causes dark urine. During treatment, it prohibits the use of alcoholic beverages in order to prevent the development of intestinal colic, nausea, vomiting.

Cooperation