Warfarin

When ATH:
B01AA03

Pharmacological action

Warfarin contains elements, do not allow the blood to clot. The drug inhibits the action of vitamin K, He took an active part in the coagulation blood. This reduces the likelihood of blood clots (blood clots).

Vein thrombosis doctors often prescribe it to treat indirect anticoagulants. This is necessary to prevent a recurrence of blood clots, which may adversely affect the general condition of the body and lead to disastrous consequences or complications. The risk of thrombosis remains high for about a year after the first case.

Before the appointment of the drug carried out a detailed survey, which allows you to identify possible side effects, and appropriate treatment.

Per day, usually, It is required to take to 5 milligrams of the drug. If adjustment is needed treatment, appoint another dose of medicine. It is worth to have a small notebook for records of doses taken, INR, side effects. These data may be useful in treating physician.

Tablets are recommended to wash down with water and taken twice a day. It is desirable to use warfarin with food. It is also important to consider, that at the initial stage of treatment is not recommended to take the drug in the "stress" doses, i.e. at doses, exceeding 5 milligram.

Indications

Vein thrombosis and predisposition to them, as well as prophylactic treatment of thrombosis and thromboembolism. Short-term indications for treatment are acute venous thrombosis and pulmonary embolism, postoperative thrombosis, acute myocardial infarction, surgical and thrombolytic treatment of thrombosis, in the case of atrial fibrillation for cardioversion. Long-term treatment is recommended in patients with recurrent venous thrombosis, prosthetic heart valves and blood vessels, transient ischemic attacks and a number of other indications, which identifies physician.

Mode of application

Treatment is carried out within 6-12 months. Selection of the optimal dosage is carried out by 2 weeks before 2 months.

Side effects

Black tarry stool color and digestive disorders; bleeding from the nose or gums; heavy and prolonged menstrual flow; increase in liver enzymes; occur for no apparent reason swelling and bruises on various parts of the body; the appearance of skin blemishes on the hips, abdominal wall, breast; hemorrhage; eczema; hair loss.

Contraindications

Their little, but it is not necessary to prescribe a drug, if you have acute bleeding, expressed violations of the liver and kidneys, there is an acute hypertension. Pregnancy is also a contraindication to warfarin.

Pregnancy

Pregnancy is a contraindication to administration of the drug. It is also recommended to stop breast-feeding in the first three days of dosing.

Interaction with other drugs

The use of almost any drug can affect the absorption of warfarin. However, most often take into account the patient receiving antibiotics and oral antidiabetic agents.

Overdose

If overdose, may start bleeding and excessive bleeding.

Storage conditions

Dry, dark place at room temperature.