Tiamazol

When ATH:
H03BB02

Characteristic.

White or yellow crystalline powder with low specific smell and bitter taste. The easily soluble in water and alcohol.

Pharmacological action.
Antitireoidnoe.

Application.

Toxic goiter, hyperthyroidism, hyperthyroidism (Graves's disease), disseminated autonomy of the thyroid gland; Preparation for surgery for goiter; Preliminary and intermediate treatment of radioactive iodine therapy.

Contraindications.

Hypersensitivity, severe leukopenia, granulocytopenia, incl. drug-induced, pregnancy, very large goiter, JavaScript nodes gland, retrosternal goiter location, lactation (optional waiver of breastfeeding).

Side effects.

Nausea, vomiting, abnormal liver function, headache, fever, joint pain, muscle, leukopenia, agranulocytosis, aplasticheskaya anemia, strumogenny effect, gipotireoz, an increase in postoperative bleeding thyroid, allergic skin reactions.

Cooperation.

The effect increases lithium preparations, beta-blockers (especially in preparation for subtotal thyroidectomy), reserpine, Amiodarone. The risk of leucopenia is increased Amidopyrine and sulfonamides.

Dosing and Administration.

Inside - 40-60 mg / day, with mild thyrotoxicosis - 30 mg / day (mono- or 4 admission) within 2-3.5 weeks. Since the onset of the euthyroid state the dose gradually (for an average of 3-8 weeks) reduced to a maintenance (5-10 Mg /), reception which lasts up to 1-1.5 years.

Cautions.

Too early termination of treatment possible relapse. It is undesirable if it is impossible to treat the regular medical control.

Cooperation