Pikovit D (Pills, coated)

Active material: Multivitamin preparations
When ATH: A11AA03
CCF: Multivitamins with macro
ICD-10 codes (testimony): E50-E64, Z54, Z73.0, Z73.3
When CSF: 17.03.02
Manufacturer: KRKA d.d. (Slovenia)

PHARMACEUTICAL FORM, COMPOSITION AND PACKAGING

◊ Pills, coated light yellow, orange, green or reddish-brown, round, lenticular; allowed blotches.

Excipients: mannitol, raspberry flavor, polysorbate 80, glycerol, castor oil, maltitol (as 75% r-ra), magnesium stearate, wax emulsion (Capone 600 farm), povidone, Colloidal anhydrous silica, maltitol, butylhydroxyanisole and butylhydroxytoluene (consisting of retinol palmitate), D,L-a-Tocopherol and medium-chain triglycerides (composed kolekaltsiferola).

1 tablet yellow further comprising: Titanium dioxide (E171) and betakaroten 1% CWS (E 160a).
1 orange tablet further comprising: Titanium dioxide (E 171) and betakaroten 10 % CWS ( E 160а).
1 tablet green further comprising: dye indigo carmine (E 132), quinoline yellow dye (E104), Titanium dioxide (E171).
1 red pill further comprising: iron oxide red dye (E 172).

10 PC. – blisters (3) – packs cardboard.

Pharmacological action

Multivitamins with macro. Pikovit^® D comprises 10 the most important vitamins, and calcium and phosphorus.

B vitamins (IN₁, IN₂, IN₆, B₁₂, pantothenic acid, nicotinamide) involved in the metabolism of carbohydrates, protein and fat.

Folic acid (vitamin B_from) inactive, however, in the body it is converted to a biologically active coenzyme – tetrahydrofolic acid, which is required for the biosynthesis of nucleic acids. It enhances growth and is involved in the maturation of erythrocytes. Folic acid is involved in the formation and recovery of platelets and their functions.

Retinol (Vitamin A) required for the development of epithelial cells and the synthesis of the visual pigment.

Kolekaltsiferol (vitamin D) involved in the metabolism of calcium and facilitates the correct mineralization of bones and teeth.

Vitamin C (vitamin C) It accelerates the absorption of iron and is involved in many redox processes in the body.

Calcium and phosphorus play a key role in the mineralization of bones and teeth. Calcium ions activate many enzymes, they are involved in the regulation of heart muscle tone, in the transmission of nerve impulses is controlled and the permeability of cell membranes.

Water-soluble vitamins (B vitamins, Vitamin C and Biotin) well absorbed in amounts, corresponding to daily needs of the organism. Quantity, exceeding the level of saturation of the tissues, the kidneys and, less, through blood.

After ingestion soluble vitamins A and D are well absorbed from the small intestine in the presence of fat. Higher amounts of fat-soluble vitamins in the liver and accumulate, so, They are more toxic, than water-soluble vitamins.

Vitamin and mineral pills Pikovit^® A does not contain sugar.

The preparation comprises sweetening agent maltitol and mannitol, which do not adversely affect the teeth.

Pharmacokinetics

Effect of the drug Pikovit^® D is a combination of its components, is a kinetic observation is not possible. All components can be traced using markers or research.

Testimony

States, accompanied by an increased need for vitamins in children, calcium and phosphorus:

- The reduction or loss of appetite;

- Fatigue in school children;

- As an adjuvant therapy with antibiotics;

- Inadequate and unbalanced nutrition (incl. as a result of inadequate intake of fresh fruits and vegetables).

Dosage regimen

Use of the drug in children under the age of 14 years – on doctor's advice.

In children aged 4 to 6 years apply for 1 tab. 4-5 time / day.

In children aged 7 to 14 years apply for 1 tab. 5-7 time / day.

The tablets should be kept in the mouth until complete dissolution.

The duration of treatment is 1 month. The need for more long-term use of the drug is determined by a physician.

Side effect

Other: in excess of the recommended dose – diarrhea (due to the presence of the drug in the composition 0.9 g maltitol); allergic reactions (stop taking the drug, consult a doctor).

Contraindications

- Hypervitaminosis A;

- hypervitaminosis D;

- Severe renal insufficiency (CC<30 ml / min);

- Children under 4 years;

- Hypersensitivity to the drug.

Pregnancy and lactation

Data on the use of the drug during pregnancy and lactation are not provided.

Cautions

Do not give children a higher dose, than recommended.

Long-term administration of the drug in high doses may cause hypervitaminosis A and D, Although the likelihood of an overdose is minimal.

If necessary, the simultaneous use of other multivitamin-mineral supplements should consult with a doctor.

Patients with diabetes mellitus may take Pikovit^® D. But it should be remembered, what 1 tablet contains 0.9 g maltitol, ie. daily dose is 3.6-6.3 g maltitol. For maltitol need insulin metabolism, although due to the slow hydrolysis and absorption in the gastrointestinal tract, the need for insulin is low. Energy value of maltitol (10 kJ / g or 2.4 kcal / g) less, than sucrose.

Overdose

Symptoms: long-term use of the drug (>1 Months) high doses can hypervitaminosis A and D. With prolonged use of vitamin B₆ high doses can peripheral neuropathy. Mannitol and maltitol enough absorbed in the digestive tract and in high doses can cause diarrhea and flatulence. Laxative effect develops when receiving maltitol >60 g / day (66 tab., coated) or mannitol >10 g / day (68 tab., coated).

Treatment: simptomaticheskaya therapy.

Drug Interactions

The data on drug interactions of the drug is not provided.

Conditions of supply of pharmacies

The drug is resolved to application as an agent Valium holidays.

Conditions and terms

The drug should be stored out of reach of children, dry, dark place at a temperature no higher than 30 ° C. Shelf life – 3 year.