Nicotinamide – Vitamin B3

When ATH: A11HA01

Pharmacological action

Vitamin PP (vitamin B3). At deficiency or absence of vitamin E in the diet developed pellagra. Nicotinamide does not have pronounced vasodilating action, and its application has not Blush skin and feeling a rush of blood to the head.

Pharmacokinetics

It is rapidly distributed to all tissues. It penetrates through the placenta and breast milk. It is metabolized in the liver with the formation of nicotinamide-N-methylnicotinamide. Report the news.

Testimony

Prevention and treatment of pellagra, gepatitы, gastritis with low acidity, kolity, atherosclerosis, vyalozazhivayuschie wounds and ulcers, infectious diseases.

Dosage regimen

Is inside after eating. In order to prevent adult – by 15-25 mg 1-2, children – 5-10 mg 1-2 When pellagra adults – by 50-100 mg 3-4, children – by 10-50 mg 2-3 during 15-20 days. In other diseases for adults – by 20-50 mg 2-3 and 5-10 mg for children 2-3

Side effect

Maybe: allergic reactions; with long-term administration at high doses – the development of fatty liver.

Contraindications

Severe forms of hypertension and angina, increased sensitivity to the nicotinamide.

Cautions

It is used as monotherapy and as part of vitamin complexes.

To prevent the development of long-term appointment at the fatty liver is recommended to include in the diet foods, rich in methionine, or designate methionine and other lipotropics.