Pyrantel

When ATH:
P02CC01

Characteristic.

Pyrantel embonate is a sandy-yellow to intense yellow-green powder with a slight characteristic odor.. Under the influence of light darkens and decomposes. Highly it is soluble in methanol, insoluble in water.

Pharmacological action.
Anthelmintic.

Application.

Askaridoz, эnterobyoz, ankylostomydoz, necatoriasis.

Contraindications.

Hypersensitivity, myasthenia, hepatic failure.

Restrictions apply.

Childhood (to 6 Months).

Pregnancy and breast-feeding.

When pregnancy is applied in case of emergency (only under strict medical supervision). At the time of treatment should stop breastfeeding (pyrantel passes into breast milk).

Side effects.

From the nervous system and sensory organs: headache, dizziness, drowsiness / insomnia, weakness; in some cases - hearing loss, hallucinations, confusion, paresthesia.

From the digestive tract: nausea, vomiting, diarrhea, stomach ache, anorexia, a slight transient increase in liver transaminases.

Allergic reactions: itch, hives, rash.

Cooperation.

Not recommended simultaneous appointment with levamisole and piperazine. Pyrantel increases the concentration of theophylline in plasma.

Overdose.

Treatment: gastric lavage. No specific antidote.

Dosing and Administration.

Inside. The dose and dosing frequency determined individually, depending on the evidence, age and body weight of the patient. When ascariasis and enterobioze designate single rate of 10 mg / kg: adults and children over 12 years - 750 mg (body weight more 75 kg - 1 g); Children up to 12 years - depending on the age. In order to avoid a repetition rate samoinvazii recommended by 3 weeks after the first dose. In case of hookworm - 10 mg / kg 1 Reception for 3 days. When necatoriasis (severe) - 20 mg / kg / day for 2 days.

Cautions.

In the case of existing liver disease should inform your doctor. After receiving a laxative pyrantel not appointed. When enterobioze should conduct simultaneous treatment of all people living together (infection is often asymptomatic). After completing the course you must control study of feces for the presence of helminth eggs. To prevent re-infection should be strictly observe the rules of hygiene (Wash hands, trim and clean your nails, to avoid scratching the perineum, daily changing bed linen and underwear).

Cooperation