Tetracycline (When ATH A01AB13)
When ATH: A01AB13
Characteristic.
Yellow crystalline powder, bitter taste. Very slightly soluble in water, hard alcohol, readily soluble in solutions of strong acids and alkalis. Hygroscopic. In the light darkens.
Pharmacological action.
Antimicrobial, Antibacterial, bacteriostatic.
Application.
Actinomycosis, bronchitis, pneumonia, Brucellosis, conjunctivitis, urinary tract infections, gingivitis, stomatitis, otitis media, pharyngitis, sinusitis, psittacosis, blue disease, Q fever, syphilis, trachoma, dysentery, sore throat, pertussis, scarlet fever, gonorrhea, tulyaremiya, typhus, bacterial endocarditis, purulent meningitis, cholecystitis, infections of skin and soft tissue.
Contraindications.
Hypersensitivity, the liver and kidneys, pregnancy, lactation (the period of treatment stop breastfeeding), childhood (to 8 years).
Side effects.
Dyspepsia, liver and kidney damage, pancreatitis, dizziness, photophobia, unsteadiness of gait, leather pigmentation, mucosas, tooth enamel in children, intracranial hypertension, dysbiosis, gipovitaminoz, photosensitivity, allergic reactions.
Cooperation.
Antacids, calcium salt, Magnesium, gland, cholestyramine - reduce the absorption from the gastrointestinal tract. Reduces the effectiveness of oral contraceptives increases the risk of uterine bleeding, reduces the activity of microbicides. Increases methoxyflurane nephrotoxicity. When combined with vitamin A increases the risk of intracranial hypertension.
Dosing and Administration.
Inside, adults - 250-500 mg 4 once a day. For children over 8 years - 6,25-12,5 mg / kg every 6 h or 12.5-25 mg / kg every 12 no. The course of treatment - 5-7 days. External used several times a day, if necessary, impose weak bandage. Intrakonyunktivalno, 3-5 Times per day.
Cooperation
Active substance | Description of interaction |
Algeldrat + Magnesium hydroxide | FKV. Slows absorption (the interval between doses should be at least 2 no). |
Amoksiцillin + Clavulanic acid | FMR. Against the background of the effect of tetracycline is weakened. |
Ampicillin + Oxacillin | FMR. Against the background of the effect of tetracycline is weakened. |