STOPTUSSIN
Active material: Butamirat, Guaifenesin
When ATH: R05FB02
CCF: Antitussive drug with a bronchodilator and expectorant
ICD-10 codes (testimony): R05
When CSF: 12.02.04.10
Manufacturer: IVAX Pharmaceuticals s.r.o. (Czech Republic)
Pharmaceutical form, composition and packaging
◊ Pills round, white, a break line.
| 1 tab. | |
| guaifenesin | 100 mg |
| Butamirate digidrogencitrat | 4 mg |
Excipients: colloidal silicon dioxide, mannitol, microcrystalline cellulose, glyceryl tribegenat, magnesium stearate.
10 PC. – blisters (2) – cardboard boxes.
◊ Drops for intake in the form of a transparent, viscous fluid from yellow to yellowish brown.
| 1 ml | 1 fl. | |
| guaifenesin | 100 mg | 1 g |
| Butamirate digidrogencitrat | 4 mg | 40 mg |
Excipients: ethanol 96%, Purified water, aroma of alpine flowers, polysorbate 80, Licorice extract liquid, propylene glycol.
10 ml – vials of dark glass (1) polyethylene dropper – cardboard boxes.
25 ml – vials of dark glass (1) polyethylene dropper – cardboard boxes.
50 ml – vials of dark glass (1) polyethylene dropper – cardboard boxes.
Pharmacological action
Combined preparation, providing mucolytic (expectorant) and antitussive effect. Part of the preparation butamirata citrate has mestnoanesteziruyuschee effect on the mucous membrane of the bronchi, providing antitussive effect. Besides, He has mild bronchodilator effect. Gvayfenezin reduces the viscosity of mucus and thereby improves its expectoration.
Pharmacokinetics
Data on the pharmacokinetics Stoptussin not provided.
Testimony
- Dry irritating cough (incl. in infectious and inflammatory diseases of the upper and lower respiratory tract);
- To eliminate the cough before- and postoperative period (tablets).
Dosage regimen
The drug should preferably be taken after meals.
Tablets should be taken with liquid, with some liquid (water, tea, fruit juice).
The appropriate amount is dissolved in the droplets 100 ml of liquid (water, tea, fruit juice).
Dose depends on the body weight of the patient:
| Body Weight | The dose and frequency of | |
| tablets | Drops for oral administration | |
| To 7 kg | – | by 8 drop. 3-4 times / day |
| 7-12 kg | – | by 9 drop. 3-4 times / day |
| 12-20 kg | – | by 14 drop. 3 times / day |
| 20-30 kg | – | by 14 drop. 3-4 times / day |
| 30-40 kg | – | by 16 drop. 3-4 times / day |
| to 50 kg | by 0.5 tab. 4 times / day | by 25 drop. 3 times / day |
| 50-70 kg | by 1 tab. 3 times / day | by 30 drop. 3 times / day |
| 70-90 kg | by 1.5 tab. 3 times / day | by 40 drop. 3 times / day |
| more 90 kg | by 1.5 tab. 4 times / day | – |
The interval between doses should be 4-6 no.
Side effect
Under the recommended dosing regimen drug, usually, well tolerated.
From the digestive system: rarely – nausea, vomiting, diarrhea, stomach ache.
CNS: rarely – dizziness, headache, drowsiness.
Allergic reactions: rarely – hives, skin rash.
Contraindications
- Myasthenia;
- Children up to age 1 year (drops);
- Children up to age 12 years (tablets);
- I trimester of pregnancy;
- Lactation;
- Hypersensitivity to the drug.
Pregnancy and lactation
Stoptussin should not be given in the I trimester of pregnancy, for use in subsequent trimesters should be especially important grounds.
Unknown, Whether stand butamirata citrate and guaifenesin in breast milk in humans. Therefore, the drug Stoptussin lactation should be vital evidence.
Cautions
In the period of treatment is not recommended to drink alcohol.
Effects on ability to drive vehicles and management mechanisms
The drug in high doses can have adverse effects on the activity of, requires more attention, coordination and rapid decision-making (eg, drive, maintenance of machinery and high-altitude work).
Overdose
Symptoms: signs of toxic effects of guaifenesin – drowsiness, nausea and vomiting.
Treatment: gastric lavage, administration of activated charcoal, simptomaticheskaya therapy, guaifenesin specific antidote does not exist.
Drug Interactions
Action guaifenesin enhanced drugs lithium and magnesium.
Guaifenesin increases the analgesic effect of paracetamol and aspirin; It enhances the effect of sedatives, hypnotics and general anesthetics on the central nervous system; effect of muscle relaxants, ethanol.
Conditions of supply of pharmacies
The drug is resolved to application as an agent Valium holidays.
Conditions and terms
The drug is in the form of tablets should be stored out of reach of children, dark place at a temperature no higher than 25 ° C. Shelf life – 4 year.
The drug is in the form of oral drops should be stored out of reach of children, dark place at a temperature of 10 ° to 25 ° C. Shelf life – 5 years.
