Cromoglicic acid (When ATH R03BC01)

When ATH:
R03BC01

Pharmacological action.
Membrane stabilizing, antiallergic.

Application.

Inhaled forms: bronchial asthma, incl. atopic, physical effort and asthmatic Triada, chronic bronchitis with a broncho-obstructive syndrome.

Capsules: alimentary allergy (if to prove the presence of antigen, separately or in combination with diet, limiting the flow of the allergen), as an adjuvant: nespetsificheskiy yazvennыy colitis, proctitis, coloproctitis; mastocytosis.

Nazalynыy spray: perennial and seasonal allergic rhinitis, pollen disease.

Eye drops: acute and chronic allergic conjunctivitis, allergic keratitis, keratokonъyunktyvyt, Syndrome of "dry eye", stress and eye fatigue, eye irritation, due to allergic reactions (Environmental factors, occupational hazard, household chemicals, cosmetics, Ophthalmic formulations, plants and pets).

Contraindications.

Hypersensitivity (incl. to benzalkonium hydrochloride), pregnancy, lactation, Children up to age 2 years (for measured aerosol — to 5 years).

Restrictions apply.

Availability nasal polyps (for intranasal forms)

Pregnancy and breast-feeding.

Contraindicated (especially in the I trimester of pregnancy). At the time of treatment should stop breastfeeding.

Side effects.

When inhalation use:

For the skin: rash, dermatitis; rarely, urticaria; in some cases, vascular edema, photodermatitis, exfoliative dermatitis.

From the nervous system and sensory organs: in some cases, malaise, dizziness, irritability, insomnia, hallucinations, tremor, peripheral neuritis, noise in ears.

From the digestive tract: nausea, gastroenteritis; in some cases, bad taste in the mouth, stomatitis, glossitis, swelling of the parotid gland, esophagism, dyspepsia, flatulence, abdominal pain, diarrhea, constipation, abnormal liver function.

With the genitourinary system: frequent urination, nephropathy.

From the respiratory system: irritation of the bronchi by inhalation (cough, retch, brief spasm; rarely is pronounced with declining indicators of external respiration, requiring discontinuation of the drug), pharyngitis; very rarely, hemoptysis, laryngeal edema, eosinophilic pneumonia.

Cardio-vascular system: in some cases, chest pain, periarterialynыy vasculitis, heart failure, perikardit, gipotenziya, irregular heartbeat.

On the part of the musculoskeletal system: myositis, in some cases, muscle and joint pain, polimiozit, swelling of joints.

Other: rarely, savorotocnaya disease.

If ingestion:

From the digestive tract: nausea, vomiting, feeling of abdominal discomfort, diarrhea.

Other: skin rash, joint pain.

When administered intranasally:

From the digestive tract: an unpleasant taste in the mouth, swelling of the tongue.

From the respiratory system: short-term irritation and increased secretions from the nose; very rarely, bleeding from the nose, ulceration of the mucous membranes of the nasal cavity, cough, suffocation.

Other: headache, arthralgia, anaphylactic reaction (cough, swallowing disorder, itchy skin, swelling of the face, lips or eyelids, labored breathing), rash, hives.

For eye drops is short-term pain and impaired vision, conjunctival hyperemia, lacrimation, swelling of the conjunctiva, foreign body sensation in the eye, dry eye, barley.

Cooperation.

Beta-adrenergic agonist, glucocorticoids, antihistamines and potentiate the effect of theophylline. It should not be inhaled Bromhexinum, ambroxol mixed with a solution of cromoglicic acid.

Dosing and Administration.

Inhalation: in bronchial asthma-adults and children over the age of 5 years (metered aerosol) at the beginning of treatment is for 1-2 doses 4-6 (to 8) once a day. For the prevention of exercise-induced asthma just before physical work can be carried out supplementation drug. In severe cases, 2 dose 6-8 times a day, When clinical improvement is on 1 dose 4 once a day. Inside, adults and children (senior 12 years) by 2 caps. (200 mg) 4 times a day for half an hour before eating and sleeping. Children from 2 to 12 years - 1 caps. (100 mg) 4 once a day (to 40 mg / kg / day). Intranasal - By 1 aerosol dose in each nostril 3-4 times a day. Eye drops: konъyunktyvalno, adults and children — by 1-2 drops 4 once a day (6-8 times) at regular intervals (when the effect of the interval between the application of gradually lengthen).

Precautions.

Be wary appoint patients with impaired hepatic or renal function. Treatment is continued until, Allergenic effect is a factor. Abolition of the drug should be carried out, gradually reducing the dose for 1 Sun. Cough, occurring after inhalation, possible to stop taking a glass of water. If the use of the drug causes recurring bronchospasm, recommended pre-inhalation bronchodilators. If concomitant therapy with bronchodilators they are used before inhalation kromoglitsievoy acid.

In the presence of benzalkonium chloride eyedrops (preservative) should not wear soft contact lenses during treatment. Hard lens is recommended for shooting 15 minutes before the instillation. It should be taken into account, after instillation of the eye is observed transient blurred vision (should not just do the job, requires more attention).

Cautions.

Not intended for relief of acute attacks of asthma and status asthmaticus. The patient must be advised of the need for regular use of the drug. Inhalation solution should be carried out using compression, or a piezoelectric ultrasonic nebulizer through a face mask or mouthpiece. Aerosol can must be shaken before use, during inhalation-keep upright (metering valve must be at the bottom). Inhalation of the contents of the capsule is carried out by a special pocket turboingalyatora ("Spïnxaler"), which put the capsule in preparation. Click on the cover of the inhaler, pierce the capsule and with the active respiratory effort of the patient to inhale the powder enters the respiratory tract.

Cooperation