Amʙroksol
When ATH:
R05CB06
Characteristic.
The white crystalline powder;, slightly bitter taste.
Pharmacological action.
Mucolytic, expectorant.
Application.
Bronchitis, pneumonia and bronchial asthma with obstruction of sputum discharge, bronchiectasis, Respiratory distress syndrome in premature infants and neonates.
Contraindications.
Hypersensitivity, gastric ulcer and duodenal ulcer, pregnancy (I trimester), lactation.
Restrictions apply.
Pregnancy (II and III trimester).
Pregnancy and breast-feeding.
It contraindicated in I trimester of pregnancy, II and III trimester of possible, if the effect of therapy outweighs the potential risk to the fetus. At the time of treatment should stop breastfeeding.
Side effects.
Weakness, headache, gastralgia, nausea, vomiting, diarrhea, rash; with the rapid on/in the introduction-intense headaches, adinamija.
Cooperation.
Increases penetration in bronchial secretion of amoxicillin, tsefuroksyma, erythromycin and doxycycline. Solution for injection pharmaceutically incompatible (in the same syringe) with the drug solution, pH exceeds 6,3.
Dosing and Administration.
Pills: adults-inwards after eating, in the first 2-3 days 1 Table. 3 once a day, then 1 Table. 2 fold or 0,5 Table. 3 once a day; children aged 5-12 years- 0,5 Table. 23 times per day.
Retard Capsules: adults and children over 12 years - 1 caps. daily.
Solution for oral and inhalation: adults inside- 4 ml 3 twice a day for 2-3 days, then - 4 ml 2 times or 2 ml 3 once a day; Children up to 2 years - 1 ml 2 once a day, 2-5 years - 1 ml 3 once a day, 5-12 years - 2 ml 2-3 times a day.
Inhalation: adults and children over 5 years — 1-2 inhalations per day for 2-3 ml, Children up to 5 years — 1-2 inhalations per day 2 ml.
Syrup: adults in the first 2-3 days 10 ml 3 once a day, then 10 ml 2 times a day, or 5 ml 3 once a day; Children up to 2 years - 2,5 ml 2 once a day, 2-5 years - 2,5 ml 3 once a day, 5-12 years - 5 ml 2-3 times a day.
Solution for injection: / m, n / a or I / (slow bolus or infusion): adults - 2 ml (in severe cases, to 4 ml) 23 times per day; daily dose at the rate of 1.2-1.6 mg/kg body weight. The solvent used 0,9% sodium chloride, 5% glucose, etc. — with a pH no higher than 6,3.
Precautions.
It should not be combined with others. antitussives, hampering the removal of sputum.
Cautions.
It is necessary to take into account, what 5 ml syrup contain sorbit and saccharine in quantity, appropriate 0,18 HE (may have implications for patients with diabetes).
Cooperation
Active substance | Description of interaction |
Amoksiцillin | FKV. Against the backdrop of increasing the concentration of ambroxol in bronchial secretions. |
Doxycycline | FKV. Against the backdrop of increasing the concentration of ambroxol in bronchial secretions. |
Cefuroxime | FKV. Against the backdrop of increasing the concentration of ambroxol in bronchial secretions. |
Erythromycin | FKV. Against the backdrop of increasing the concentration of ambroxol in bronchial secretions. |