Fenoterol (When ATH R03CC04)
When ATH:
R03CC04
Pharmacological action.
Bronchodilator, tokoliticheskoe.
Application.
Bronchial asthma, asthmatic bronchitis, emphysema, fibrosis, threat of premature delivery.
Contraindications.
Hypersensitivity, heart disease, arrhythmia, CHD, decompensated diabetes, thyrotoxicosis, glaucoma, asthmatic status, pregnancy (I trimester).
Restrictions apply.
Pregnancy (II and III trimester), lactation, childhood (to 6 years).
Pregnancy and breast-feeding.
It contraindicated in I trimester of pregnancy. In II and III trimester of pregnancy, as well as through breast-feeding may, if the effect of therapy outweighs the potential risk to the fetus or child.
Side effects.
From the nervous system and sensory organs: hand tremor, dizziness, headache, nervousness, weakness.
Cardio-vascular system and blood (hematopoiesis, hemostasis): tachycardia, heartbeat; using high doses - lowering and raising Sad Dad, arrhythmia.
From the side of respiratory system: cough, paradoxical bronchospasm.
From the digestive tract: nausea, vomiting.
Other: Sweating, myalgia and muscle spasm, kaliopenia, allergic reactions.
Cooperation.
MAO inhibitors, tricyclic antidepressants, anticholinergics, ksantinы (theophylline), corticosteroids, Diuretic, other beta-agonists may increase the effects of, incl. side (especially if hypokalemia). Halogenated hydrocarbon anesthetics (halothane, trichlorethylene, enfluran) potentiate the effect on the cardiovascular system. Beta-blockers significantly attenuate Activity.
Overdose.
Symptoms: tachycardia, heartbeat, arterial hyper- or hypotension, an increase in pulse pressure, anginal pain, arrhythmia, flushing, tremor.
Treatment: use of sedatives, trankvilizatorov, in severe cases - intensive care. As an antidote recommended cardioselective beta-blockers (atenolol et al.).
Dosing and Administration.
Inhalation: adult, by 0,2 mg 1-3 times a day, children 6-12 years - 0,1 m
g 1-3 times per day. With the threat of miscarriage: I /, 0,5 mg dissolved in 250-300 ml 5% glucose solution, administered at a rate of 15-20 drops per minute to inhibition of uterine contractile activity, then inward 5 mg every 3-6 hours, The maximum daily dose - 40 mg.
Cooperation
Active substance | Description of interaction |
Aminofillin | FMR: synergism. Strengthens (mutually) bronchodilator effect, It increases the risk of hypokalemia. |
Halothane | FMR: synergism. Strengthens (mutually) negative effect on the cardiovascular system. |
Theophylline | FMR: synergism. Do effects, incl. side (particularly the likelihood of hypokalemia). |