Drotaverine: characteristic, instructions for use, structure, Contraindications
When ATH: A03AD02
Drotaverine: characteristic
Crystalline powder of light yellow color, without smell. Soluble in water and alcohol.
Drotaverine: pharmachologic effect
Spasmolytic, myotropic, vasodilator, gipotenzivnoe.
Drotaverine: application
Spasm of smooth muscles of internal organs (Cardio- and pilorospazm), chronic gastro, gastric ulcer and duodenal ulcer, cholelithiasis (pečenočnaâ how), chronic cholecystitis, postcholecystectomical syndrome, gipermotornaya biliary dyskinesia, spasticheskaya dyskinesia kishechnika, intestinal colic due to the delay of gases after surgery, colitis, proctitis, tenesmus, flatulence, urolithiasis disease (počečnaâ how), pyelitis, cerebral vasospasm, coronary and peripheral arteries, the need to reduce uterine contractions and cervical spasm relief during childbirth, smooth muscle spasm during the instrumental interventions.
Drotaverine: Contraindications
Hypersensitivity, glaucoma.
Drotaverine: restrictions on use
Prostate adenoma, expressed atherosclerosis of the coronary arteries.
Drotaverine: side effects
Feeling the heat, dizziness, Arrhythmia, gipotenziya, heartbeat, Sweating (often at parenteral administration), atopic dermatitis.
Drotaverine: interaction
Strengthens (especially when on / in) the effect of other spasmolytics (incl. Mr. holinoblokatorov), gipotenziю, caused by tricyclic antidepressants, xinidinom, novokainamidom. Reliability eliminate spasm increases phenobarbital. It reduces the activity of morphine spasmogenic, antiparkinsonian properties of levodopa.
Drotaverine: overdose
OF блокада, cardiac arrest, paralysis of the respiratory center.
Drotaverine: Dosing and Administration
Inside - on 0,04-0,08 g 2-3 times a day. / M, n / k - 2-4 ml 1-3 times a day, to relieve colic - in / in slowly, 2-4 ml. Children up 6 years - 0,01-0,02 g 1-2 times per day, children 6-12 years old - 0,02 g 1-2 times per day.
Cooperation
Active substance | Description of interaction |
Morphine | FMR: antagonizm. Against the background of reduced drotaverine spasmogens Activity. |
Prokaynamyd | FMR: synergism. Strengthens (mutually) gipotenziю. |
Phenobarbital | FMR: synergism. Enhances antispasmodic effect. |
Quinidine | FMR: synergism. Strengthens (mutually) gipotenziю. |