Drotaverine: characteristic, instructions for use, structure, Contraindications

When ATH: A03AD02

Drotaverine: characteristic

Crystalline powder of light yellow color, without smell. Soluble in water and alcohol.

Drotaverine: pharmachologic effect

Spasmolytic, myotropic, vasodilator, gipotenzivnoe.

Drotaverine: application

Spasm of smooth muscles of internal organs (Cardio- and pilorospazm), chronic gastro, gastric ulcer and duodenal ulcer, cholelithiasis (pečenočnaâ how), chronic cholecystitis, postcholecystectomical syndrome, gipermotornaya biliary dyskinesia, spasticheskaya dyskinesia kishechnika, intestinal colic due to the delay of gases after surgery, colitis, proctitis, tenesmus, flatulence, urolithiasis disease (počečnaâ how), pyelitis, cerebral vasospasm, coronary and peripheral arteries, the need to reduce uterine contractions and cervical spasm relief during childbirth, smooth muscle spasm during the instrumental interventions.

Drotaverine: Contraindications

Hypersensitivity, glaucoma.

Drotaverine: restrictions on use

Prostate adenoma, expressed atherosclerosis of the coronary arteries.

Drotaverine: side effects

Feeling the heat, dizziness, Arrhythmia, gipotenziya, heartbeat, Sweating (often at parenteral administration), atopic dermatitis.

Drotaverine: interaction

Strengthens (especially when on / in) the effect of other spasmolytics (incl. Mr. holinoblokatorov), gipotenziю, caused by tricyclic antidepressants, xinidinom, novokainamidom. Reliability eliminate spasm increases phenobarbital. It reduces the activity of morphine spasmogenic, antiparkinsonian properties of levodopa.

Drotaverine: overdose

OF блокада, cardiac arrest, paralysis of the respiratory center.

Drotaverine: Dosing and Administration

Inside - on 0,04-0,08 g 2-3 times a day. / M, n / k - 2-4 ml 1-3 times a day, to relieve colic - in / in slowly, 2-4 ml. Children up 6 years - 0,01-0,02 g 1-2 times per day, children 6-12 years old - 0,02 g 1-2 times per day.

Cooperation

Active substanceDescription of interaction
MorphineFMR: antagonizm. Against the background of reduced drotaverine spasmogens Activity.
ProkaynamydFMR: synergism. Strengthens (mutually) gipotenziю.
PhenobarbitalFMR: synergism. Enhances antispasmodic effect.
QuinidineFMR: synergism. Strengthens (mutually) gipotenziю.

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