Tseftybuten

When ATH:
J01DD14

Characteristic.

The antibiotic cephalosporin III generation.

Pharmacological action.
Antibacterial, bactericide.

Application.

Treatment of infectious and inflammatory diseases of the upper (pharyngitis, tonsillitis, scarlet fever) and lower (acute and chronic bronchitis, pneumonia) respiratory, ENT (sinusitis, otitis media), urinary tract (complicated and uncomplicated cystitis, uretrit, including gonococcal), GI (enteritis, incl. dysenteric, and gastroenteritis, caused Salmonella, Escherichia coli, Shigella, Helicobacter pylori).

Contraindications.

Hypersensitivity (incl. penicillin, carbapenems and other cephalosporins), infancy (to 6 Months).

Pregnancy and breast-feeding.

Maybe, if the effect of therapy outweighs the potential risk to the fetus and newborn.

Category actions result in FDA - B. (The study of reproduction in animals revealed no risk of adverse effects on the fetus, and adequate and well-controlled studies in pregnant women have not done.)

Side effects.

Nausea, vomiting, dyspepsia, gastritis, flatulence, belching, stomach ache, anorexia, constipation, dry mouth, taste disturbance, headache, dizziness, weakness, drowsiness, paresthesia, tinnitus; psevdomembranoznыy colitis, candidiasis, vaginitis, dizurija, breathlessness, leukopenia, eozinofilija, decrease in hemoglobin, increased liver transaminases, Alkaline phosphatase, bilirubin, creatinine, skin rash, itch, hives, angioedema; children-excitement, dehydration, fever, hematuria, hyperkinesis, insomnia, chills, ground, afazija, jaundice, toxic skin necrosis, muscle stiffness.

Overdose.

Symptoms: excitation, convulsions.

Treatment: gastric lavage, hemodialysis.

Dosing and Administration.

Inside, regardless of the meal; adults and children over 10 years 400 mg 1 once a day (When pneumonia 200 mg per day). Adult patients with renal insufficiency require dose adjustment: When Cl creatinine 30-49 mL/min 200 mg per day or 400 mg after 48 no; 29-5 mL/min — 100 mg/day or 400 mg after 96 no. Patients, hemodialysis (2-3 Treatments per week), appointed 400 mg or 9 mg/kg at the end of each dialysis. Babies (to 10 age and body weight of less than 45 kg) - 9 mg / kg per day (maximally 400 mg per day) in suspension. In the treatment of acute enteritis dose may be divided into 2 admission. Duration of treatment is 5-10 days, infections, caused Streptococcus pyogenes, - No less 10 days.

Precautions.

To use caution in patients with gastrointestinal diseases (especially chronic colitis).

Cooperation