ZINERIT

Active material: Erythromycin, Zinc acetate
When ATH: D10AF52
CCF: Drug with antibacterial and komedonoliticheskim action for the treatment of acne
ICD-10 codes (testimony): L70
When CSF: 06.07.02
Manufacturer: ASTELLAS PHARMA EUROPE B.V. (Netherlands)

Pharmaceutical form, composition and packaging

◊ Powder for solution for outdoor applications; enclosed solvent – colorless, clear.

Solvent: diizopropilsebaktat, ethanol.

Plastic Bottles (1) together with the solvent (fl. 30 ml 1 PC.) applicator – packs cardboard.

Pharmacological action

Erythromycin-zinc complex. Anti-inflammatory, antibacterial action and komedonoliticheskoe.

Erythromycin bacteriostatic effect on microorganisms, causing acne: Propionibacterium acnes Staphylococcus epidermidis и. Zinc reduces the production of sebum, anti-inflammatory effect, to avoid the development of resistance to erythromycin.

Pharmacokinetics

Integrated communications components of the drug provides a good penetration into the skin of active substances.

Zinc is mainly associated with follicular epithelium and not resorbed into the systemic circulation.

A minor part of erythromycin exposed systemic absorption and further removed from the body.

Testimony

- Acne treatment.

Dosage regimen

The drug is used topically. Using the supplied applicator prepared solution zinerita^® put a thin layer on the affected area of ​​the skin 2 times / day: morning (before applying make-up) and in the evening (after washing). Apply the drug should be by tilting the vial with the prepared solution down, with light pressure. The deposition rate of the solution is regulated pressure force applicator on the skin. Approximate single dose – 0.5 ml. After drying, the solution becomes invisible.

Course Length – 10-12 weeks. In some cases, clinical improvement occurs within 2 of the week.

Side effect

Local reactions: it may sometimes be a burning sensation, irritation, dry skin at the site of drug. Usually, these effects are mild and do not require discontinuation of the drug and / or symptomatic therapy.

Contraindications

- Hypersensitivity to erythromycin and other macrolides;

- Hypersensitivity to zinc or other ingredients.

Pregnancy and lactation

It is now established, that the use of the drug during pregnancy and lactation is possible if indicated in recommended doses.

Cautions

In applying the drug should take into account the possibility of cross-resistance to other macrolide antibiotics, lincomycin, clindamycin.

Avoid contact with the eyes or mucous membrane of the mouth and nose, tk. it can cause irritation and burns.

Overdose

Accidental overdose is unlikely due to the nature of local drug application.

Drug Interactions

To date, no clinically significant interaction found zinerita^® with other drugs.

Conditions of supply of pharmacies

The drug is resolved to application as an agent Valium holidays.

Conditions and terms

The drug should be stored out of reach of children at temperature from 15 ° to 25 ° C. Term life – 3 year.