VYZOPTYK

Active material: Tetryzolin
When ATH: S01GA02
CCF: A drug with a vasoconstrictive effect for topical use in ophthalmology
ICD-10 codes (testimony): H10.1, H10.2
When CSF: 26.05
Manufacturer: S.C. ROMPHARM Company S.R.L. (Romania)

Pharmaceutical form, composition and packaging

◊ Eye drops 0.05% in the form of a clear colorless solution.

Excipients: boric acid, sodium tetraborate decahydrate, disodium эdetata digidrat, benzalkonium chloride, Purified water.

15 ml – flakonah- polymer (1) – packs cardboard.

Pharmacological action

Alpha-agonists. Has a vasoconstrictor and anti-edematous effect.

With local use, reduces the edema of the conjunctiva, Burning sensations, Soreness of the mucous membrane of the eyes, lacrimation.

The vasoconstrictive effect develops for several minutes and persists 4-8 no.

Pharmacokinetics

When applied topically, systemic absorption is low..

Testimony

- moderate irritation of the eyes: itch, edema and hyperemia of conjunctiva, burning, lacrimation, injection sclera, caused by chemical and physical factors (dust, cosmetics, chlorinated water, the action of bright light or the radiation of a computer monitor);

- Allergic conjunctivitis.

Dosage regimen

Adults and children over 3 years instill 1-2 drops 2-3 times/day in the lower conjunctival bag of the affected eye.

If during the 48 h the improvement should not stop the further use of the drug and consult a doctor.

Side effect

Local reactions: increased intraocular pressure, stinging eyes and reactive hyperemia; rarely – mydriasis.

Systemic reactions: increased blood pressure, giperglikemiâ, Violation of the heart, headache, nausea, drowsiness, weakness, tremor, dizziness, insomnia, tachycardia, allergic reactions.

Contraindications

- Glaucoma;

— endothelial-epithelial dystrophy of the cornea;

-acute cardiovascular failure;

- Bacterial eye infection;

- Foreign body of the eye;

- Children's age (to 3 years);

- Hypersensitivity to the drug.

FROM caution the drug should be used in hypertension, Arrhythmia, — endothelial-epithelial dystrophy of the cornea, gipertireoze, pheochromocytoma, diabetes, severe organic heart disease and vascular (In), as well as during the treatment with MAO inhibitors and other drugs, increases AD.

Pregnancy and lactation

Use of the drug during pregnancy and lactation (breast-feeding) It is possible only if, If the estimated benefit for the mother exceeds the risk for the fetus or child.

Cautions

It is advisable to use a visceptic only with mild eye irritation. If irritation and conjunctival hyperemia associated with infectious disease, the presence of a foreign body or chemical injuries of the cornea, should consult an ophthalmologist.

If during the 48 h after the start of the use of eye drops, the symptoms of the disease are preserved, become more pronounced or a side effect is manifested, should stop using the product and consult an eye doctor.

When the intense pain in the eyes, headache, visual impairment, the sudden appearance of "floating spots" before the eyes, redness of the eye, Pain, when exposed to light or double in the eyes, you must immediately consult a doctor.

If you wear contact lenses they are removed before instillation of the drug and re-established through 15 minutes after the. It is necessary to avoid direct contact of eye drops with soft contact lenses because of a possible breach of transparency.

The drug should not be used simultaneously with MAO inhibitors (incl. phenelzine, nialamide, iproniazid) and for 10 days after the termination of their employment.

Effects on ability to drive vehicles and management mechanisms

During the period of treatment must be careful when driving and occupation of other potentially hazardous activities, require high concentration, psychomotor speed reactions and eyesight (After the use of eye drops, it is possible to expand the pupil and a feeling of clouding of vision).

Overdose

The development of systemic symptoms of an overdose is possible with an accidental or intentional administration of the drug inside or exceeding the dosage with local use.

Symptoms: mydriasis, nausea, cyanosis, fever, convulsions, Arrhythmia, arterial hypertension, pulmonary edema, dyspnoea. Excessive systemic absorption of imidazole derivatives can lead to inhibition of the central nervous system, accompanied by sleepiness, hypothermia, ʙradikardiej, collapse, Excessive total absorption of imidazole derivatives can lead to CNS depression.

Excessive total absorption of imidazole derivatives can lead to CNS depression, associated with drug absorption, associated with drug absorption, associated with drug absorption. Overdose in children may manifest CNS depression, accompanied by sleepiness, Excessive sweating, severe hypotension, up to the shock.

Treatment: activated charcoal, gastric lavage, associated with drug absorption, The use of antipyretic and anticonvulsants. To reduce blood pressure, pantolamine is used 5 mg 0.9% sodium solution of chloride slowly in/in or by 100 mg orally. Spetsificheskiy antidote unknown.

Drug Interactions

Concomitant use with MAO inhibitors, tricyclic antidepressants, guanetidine can cause arterial hypertension, taxikardiju.

Simultaneous use with resepin, insulinom, propranolol, General anesthetics, Atropine increases the risk of cardiovascular effects of tetrizol.

Simultaneous use with guanetidine can provoke a midriasis with a temporary visual impairment.

Conditions of supply of pharmacies

The drug is resolved to application as an agent Valium holidays.

Conditions and terms

The drug should be stored in an inaccessible place for children at a temperature of 15-25 ° C. Shelf life – 5 years.

After opening the bottle of the drop should be used during 4 weeks.