Tetryzolin (When ATH S01GA02)

When ATH:
S01GA02

Characteristic.

Tetryzoline hydrochloride - easily soluble in water, alcohol, very slightly soluble in chloroform, almost narastvorim broadcast. pH 1% an aqueous solution of 5.0-6.5. Molecular weight 236,75.

Pharmacological action.
Vasoconstrictive, antikongestivnoe.

Application.

Swelling of the conjunctiva, secondary congestion in allergic diseases of the eye, conjunctival irritation (as a result of exposure to chemical and physical factors, incl. such as smoke, dust, hlorirovannaya water, bright light, cosmetics, contact lenses), catarrhal conjunctivitis.

Swelling of the nasal mucosa in patients, suffering from rhinitis, faringitom, sinusiti, hay fever, and to reduce the swelling of the nasal mucosa in the need for diagnostic and therapeutic measures.

Contraindications.

Hypersensitivity; eye drops: severe eye disease (glaucoma, syndrome of "dry eye", эpitelialyno-эndotelialynaya dystrophy rogovitsы), Children up to age 2 years; nasal drops: dry rhinitis, Children up to age 2 years (0,05% solution), to 6 years (0,1% solution).

Restrictions apply.

Severe cardiovascular disease (incl. CHD, arrhythmia, aneurysm Serdtse, arterial hypertension), hyperthyroidism, diabetes, pheochromocytoma, During treatment drugs, increases AD, incl. MAO inhibitors.

Pregnancy and breast-feeding.

Because of the potential for systemic side effects, the use during pregnancy and lactation is possible only after a careful comparison of the potential benefits to the mother and the risk to the fetus or child. Reproductive studies in animals have not been conducted. Unknown, Do tetryzoline excreted into breast milk.

Side effects.

Eye drops: mydriasis, increased intraocular pressure, stinging eyes and reactive hyperemia.

Nasal drops: burning and tingling in the nose, chikhaniye, dry mucous membranes of the nasal cavity; long-term use or overdose - secondary swelling, hyperemia of the nasal mucosa.

Systemic effects: headache, dizziness, weakness, tremor, insomnia, increased blood pressure, heartbeat, nausea, giperglikemiâ, allergic reactions.

Cooperation.

Incompatible with MAO inhibitors (may develop hypertension).

Overdose.

Symptoms: mydriasis, nausea, cyanosis, fever, convulsions, tachycardia / bradycardia, arterial hypertension, dizziness, shock-like syndrome with hypotension and bradycardia. Overdose in children may manifest CNS depression, accompanied by sleepiness, Excessive sweating, severe hypotension, up to the shock.

Treatment: appointment of activated carbon, gastric lavage, simptomaticheskaya therapy (inhalation of oxygen, the use of fever-reducing, anticonvulsants). Spetsificheskiy antidote unknown.

Dosing and Administration.

Konъyunktyvalno, in each eye in the lower conjunctival sac - 1-2 drops 2-3 times daily. Without consulting an ophthalmologist should not be used continuously for more than 4 days. If improvement does not come within 48 no, treatment should be stopped.

Intranasal, adults and children over 6 years - 2-4 drops 0,1% solution, children 2-6 years - 2-3 drops 0,05% solution into each nostril at intervals of not less than 3 no. Do not use more than 3-5 days (except for the doctor's recommendations). Re-appointment is possible only after a few days.

Precautions.

You must strictly comply with the dosing regimen. Avoid prolonged use and overdose. With prolonged use may develop toxic effects. The risk of overdose, due to systemic absorption of the drug, high in infants and young children (especially if accidentally swallowed).

Tetryzoline in the form of eye drops is advisable to apply only in mild eye irritation. If irritation and conjunctival hyperemia associated with infectious disease, the presence of a foreign body or chemical injuries of the cornea, should consult an ophthalmologist.

If during the 48 hours after the start of application of eye drops symptoms persist / or become more pronounced side effects manifested, should stop using the product and consult an eye doctor. When the intense pain in the eyes, headache, visual impairment, the sudden appearance of floating spots before the eyes, redness of eyes, pain when exposed to light or double vision, you must seek medical advice immediately.

If you wear contact lenses they are removed before instillation of the drug and re-established through 15 minutes after the. It is necessary to avoid direct contact of eye drops with soft contact lenses because of a possible breach of transparency.

During the period of treatment must be careful when driving or operating machinery (after applying eye drops may mydriasis and the occurrence of blurred vision).