Tussin PLUS

Active material: Dextromethorphan, Guaifenesin
When ATH: R05DA20
CCF: Drug with antitussive and expectorant
When CSF:
Manufacturer: SAGMEL, Inc. (United States)


Syrup orange-red color with weak smell of cherries.

5 ml
guaifenesin100 mg
dextromethorphan gidrobromid10 mg

lemon acid, flavoring, glycerol, corn syrup high fructose, sodium saccharin, Sodium benzoate, cherry flavor, dye FD&C Red №40, water.

118 ml – PET bottles (1) complete with a measured glass – packs cardboard.

Pharmacological action

Combined preparation, provides protivokashlevoe, mucolytic and expectorant action. Dextromethorphan – antitussive, on the strength of close to kodeino. It has no narcotic, pain and hypnotic action, not oppressing breathing Centre and activity resnitchatogo epithelium, suppresses the cough of any origin. Guaifenesin – mucolytic agent, stimulates cells secretorne mucous membrane bronchi, produce neutral polysaccharides, depolimerizuet acid mucopolysaccharides, reduces viscosity and increases the amount of sputum, activates the ciliary apparatus of the bronchi, It facilitates the removal of phlegm and facilitates the transition of non-productive cough productive.



Respiratory system diseases, tussive (simptomaticheskaya therapy): “colds” disease (incl. flu, SARS), tracheitis, bronchitis (incl. complicated bronchiectasis), pulmonary tuberculosis, pneumonia, mukovystsydoz.



Hypersensitivity, heavy organic diseases of the central nervous system, peptic ulcer and 12 duodenal ulcer, bleeding from the gastrointestinal tract (incl. history), productive cough with copious sputum conversion, childhood (to 6 years).C care. Hepatic and / or renal failure, bronchial asthma, pregnancy, lactation.


Side effects

Dyspepsia (nausea, vomiting, abdominal pain), diarrhea, exacerbation of gastric ulcer and 12 duodenal ulcer, dizziness, headache, drowsiness or insomnia, hypererethism (especially in children), allergic reactions (skin rash, hives, hyperthermia).Overdose. Symptoms, due dekstrometorfanom: excitation, dizziness, respiratory depression, disturbance of consciousness, decrease in blood pressure, tachycardia, hypertonus muscles, ataxia. Symptoms, due gvajfenezinom: nausea, vomiting. Treatment: gastric lavage, appointment of activated carbon, simptomaticheskaya therapy, IVL (in severe cases).


Dosing and Administration

Babies 6-12 years – by 1 c.lojke every 4 no. Inside, every 4 no (no more 6 once a day), adults and children over 12 years – 10 ml (2 c.logki), children 6-12 years – 5 ml, 3-6 years – 2.5 ml.



During treatment, it is recommended to take plenty of fluids. It is advisable to combine with posture drainage or vibration massage chest. Perhaps staining of urine in pink. Determination results of 5-HIAA in urine (in ispolyzovanii nitrozonaftolynogo reagent) It may be falsely inflated due to the influence of metabolites of guaifenesin per color (reception should be stopped for guaifenesin 48 h to collect urine for the test). Guaifenesin and its metabolites may cause discoloration in determining vanillylmandelic acid in urine and falsely inflate test results with her catechins (reception should be stopped for guaifenesin 48 h to collect urine for the test). Should not be taken to treat permanent cough without a prescription. If the 7 days dose cough persists, or along with cough marked hyperthermia, skin rash, prolonged headache, sore throat, Talk to your doctor.



Kodeinsoderjaschie HP impede releases liquefied phlegm. Compatible with bronholitikami, antimicrobial HP, cardiac glycosides. Incompatible with HP, inhibit MAO (incl. furazolidon, procarbazine, selegiline), that the application can invoke adrenergicheskij Kriz, collapse, whom, dizziness, excitation, increased blood pressure, hyperpyrexia, intracranial hemorrhage, drowsiness, nausea, spasms, tremor. Amiodarone, fluoxetine, quinidine, ингибируя систему цитохрома P450, can increase the concentration of drug in the blood. Tobacco smoke can lead to increased secretion of glands for background inhibition of the cough reflex. Not recommended simultaneous application etc. mukolitikov.

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