Troxerutine VRAMED

Active material: Troxerutin
When ATH: C05CA04
CCF: Venous drug for external use
When CSF:
Manufacturer: SOPHARMA AD (Bulgaria)

Pharmaceutical form, composition and packaging

Gel for external use 2%1 g
troxerutin20 mg

40 g – aluminum tuba (1) – packs cardboard.

Capsules1 caps.
troxerutin300 mg

10 PC. – packings Valium planimetric (5) – packs cardboard.


Pharmacological action

Flavonoid (derivative of rutin), It has a P-vitamin activity; It has venotonic, angioprotektornoe, decongestant, antioxidant and anti-inflammatory action. Participates in the redox processes, blocks hyaluronidase, stabilizes hyaluronic acid cell membranes and reduces the permeability and capillary fragility, increases their tone. It increases the density of the vascular wall, It reduces the exudation of the liquid plasma and diapedesis of blood cells. Reduces inflammation in the vascular wall, loss of adhesion to the surface of platelets. Patients with chronic venous insufficiency is recommended application both in primary, and in the later stages of the disease. When states, characterized by increased vascular permeability (incl. scarlet fever, Flu, peel, allergic reactions), is used in combination with ascorbic acid to enhance its effect. Non-toxic, It has a greater breadth of therapeutic action.



Phlebeurysm, chronic venous insufficiency with such manifestations, as static heaviness, leg ulcers, trophic skin lesions, superficial thrombophlebitis, periphlebitis, fleʙotromʙoz, leg ulcers, dermatitis, hemorrhoids, post-thrombotic syndrome, diabetic microangiopathy, retinopathy, gyemorragichyeskii diatyez (increased capillary permeability), incl. measles, scarlet fever, Flu, Cardiovascular side effects of radiation therapy, post-traumatic edema, hematoma, prevention of complications after surgery on veins.



Hypersensitivity, peptic ulcer and 12 duodenal ulcer, chronic gastritis (exacerbation), pregnancy (I trimester), lactation. Renal failure (long-term use).


Side effects

Allergic reactions, erosive and ulcerative lesions of the gastrointestinal tract, headache.


Dosing and Administration

V / m, or in / slow, by 500 mg a day (no less 5 injection), then move on ingestion – by 600-900 mg with meals, during 2-4 weeks or more, maintenance therapy – 300 mg per day. Outwardly: gel is applied morning and evening on the skin of the painful area distal to the proximal part and lightly massage until complete absorption. The gel can be applied under an occlusive dressing.
Inside, while eating, by 1 caps. 23 times per day. For maintenance treatment - for 1 caps. a day for 3-4 weeks.



It enhances the effect of ascorbic acid on the structure and permeability of vascular wall.

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