TRAVOKORT

Active material: Diflukortolon, Isoconazole
When ATH: D07XC04
CCF: The drug with antifungal and anti-inflammatory for outdoor use
ICD-10 codes (testimony): B35.0, B35.2, B35.3, B35.4, B35.6, B36.0, B37.2, B37.3, B37.4, L08.1
When CSF: 04.05
Manufacturer: INTENDIS GmbH (Germany)

Pharmaceutical form, composition and packaging

Cream white or slightly yellowish, opaque.

Excipients: polysorbate 60, sorbitan stearate, cetylstearyl alcohol, Liquid paraffin, white petrolatum, sodium edetate, Purified water.

15 g – aluminum tuba (1) – packs cardboard.
20 g – aluminum tuba (1) – packs cardboard.
30 g – aluminum tuba (1) – packs cardboard.

Pharmacological action

Combined preparation for external use, synthetic imidazole derivative. Effective fungistatically. It is active against dermatophytes Trichophyton spp., Microsporum spp., Epidermophyton, mold, yeast and yeast-like fungi of the genus Candida, and Corynebacterium minutissium (pathogen erythrasma). Antibacterial activity against certain Gram-positive bacteria (streptococci and staphylococci).

Diflukortolona valerate - SCS for external use. Anti-inflammatory, antiexudative, antiallergic and antipruritic effect.

Pharmacokinetics

When applied to the skin absorption is negligible.

Testimony

Fungal skin lesions, incl. secondarily infected, accompanied by severe inflammatory symptoms or ekzemopodobnye:

- Tinea pedis;

- Ringworm smooth skin (incl. localized in the folds of the skin, interdigital spaces, vulva);

- Erythrasma.

Dosage regimen

Travokort applied thinly to the affected skin and gently rub: the procedure is performed 2 times / day (in the morning and at night).

After regression of inflammation Travokortom treatment should be stopped and further treatment cream travogen, does not contain corticosteroids. This is especially important when applying the product to the genital area, and inguinal folds.

The maximum duration of treatment is Travokortom 2 of the week.

Side effect

Rarely: skin irritation, allergic reactions.

Effects, due to the action of corticosteroids: when applied to large areas (more 10% skin) for a long time (more 4 weeks) and / or by using occlusive dressings can skin atrophy, teleangiэktazii, striae, akneformny dermatitis, perioral dermatitis, hypertryhoz, as well as systemic side effects (suppression of the hypothalamic-pituitary-adrenal axis) due to absorption of GCS.

Usually, Travokort well tolerated, even when applied to sensitive skin.

Contraindications

- Lupus; cutaneous manifestations of syphilis; viral skin lesions (enable vetryanaya, shingles) at the site of the drug;

- Skin reactions after vaccination at the site of the drug;

- I trimester of pregnancy;

- Hypersensitivity to the drug.

Pregnancy and lactation

Travokort (as well as other topical preparations, containing corticosteroids), not recommended for use in the I trimester of pregnancy.

Application in I and II trimesters of pregnancy is possible only in cases, when the expected benefit of therapy for the mother outweighs the potential risk to the fetus.

If necessary, use during lactation should decide the issue of termination of breastfeeding.

We can not completely exclude the development of side effects, eg, reduction of adrenocortical function, in newborn, whose mothers during pregnancy and lactation received long-term treatment or medication applied to the vast surface of the body.

Cautions

The drug is intended for external use only.

Avoid contact with the eyes and applying to open wounds.

Patients with rosacea or perioral dermatitis should avoid applying the product on the skin.

The patient must inform the doctor about the absence of a therapeutic effect, the appearance of any adverse effects during treatment Travokortom, as well as the simultaneous administration of other drugs.

Use in Pediatrics

The drug is prescribed for children 2 and older only on strict conditions and under medical supervision, tk. may develop systemic side effects, associated with the action diflukortolona.

Overdose

According to a study of acute toxicity diflukortolona valerate, isoconazole nitrate, and lotions, containing both substances, unlikely risk of acute toxicity after a single application to skin of increased dose (on a large surface at conditions, absorption promoters) or Accidental Ingestion whole package Travokorta.

Drug Interactions

Clinical trials and drug application in medical practice have not revealed incompatibilities or interactions with other drugs.

Conditions of supply of pharmacies

The drug is released under the prescription.

Conditions and terms

List B. The drug should be stored out of reach of children at or above 25 ° C. Shelf life - 5 years.