SPAKOVIN (Pills)

Active material: Drotaverine
When ATH: A03AD02
CCF: Myotropic antispasmodic
When CSF: 01.14.05
Manufacturer: M.J.BIOPHARM Pvt.Ltd. (India)

dosage form, composition and packaging

Excipients: starch, microcrystalline cellulose, povidone, magnesium stearate, talc.

10 PC. – packings Valium planimetric (2) – packs cardboard.

Excipients: starch, microcrystalline cellulose, povidone, magnesium stearate, talc.

10 PC. – packings Valium planimetric (2) – packs cardboard.

Pharmacological action

• vazodilatirtee
• antispasmodic

Ingredients – Drotaverine hydrochloride 40 mg, Excipients (starch, Cellulose mikrokristalicheskaya, polyvidone, magnesium stearate, talc) – tablets; Drotaverine hydrochloride 80 mg, Excipients (starch, Cellulose mikrokristalicheskaya, polyvidone, magnesium stearate, talc) – tablets 80 mg

Testimony

• Gastroeyunalynaya ulcer
• Arteritis unspecified
• Pain in the abdomen and pelvis
• Headache
• Pain unspecified
• Pain, not elsewhere classified
• Pain, associated with urination
• Pain and other conditions, associated with female genital organs and menstrual cycle
• Gallbladder disease, biliary tract and pancreas
• Painful urination, unspecified
• Secondary dysmenorrhea
• Constipation
• The stones of the bile duct with cholecystitis
• General symptoms and signs
• Miscarriage
• Pilorospazm, not elsewhere classified
• Počečnaâ how neutočnennaâ
• Acute cholecystitis
• Neinfektsionnыy gastroэnterit and colitis neutochnennыy
• Neinfektsionnыy эnterit and colitis
• Peptic ulcer of unspecified site
• Spontaneous abortion
• Symptoms and signs, related to the urinary system
• Symptoms and signs, related to the digestive system and abdomen
• Somatoform dysfunction of the autonomic nervous system
• Somatoform disorders
• Vascular headache, not elsewhere classified
• Vascular disease of the intestine
• Vascular disease of the intestine, unspecified
• Chronic cholecystitis
• Chronic vascular disease
• Cholecystitis
• Cholecystitis neutochnennыy
• Tenesmus bladder
• Other diseases of anus and rectum
• Other diseases of intestines
• Other diseases of esophagus
• Other diseases of the stomach and duodenum
• Other diseases of gallbladder
• Other and unspecified abdominal pain
• Other disorders of arteries and arterioles
• Other noninfectious gastroenteritis and colitis
• Other symptoms and signs, related to the digestive system and abdomen
• Other headache syndromes
• Other forms of cholecystitis
• Other functional intestinal disorders
• Other specified diseases of anus and rectum
• Other specified diseases of gallbladder
• Other specified non-infectious gastroenteritis and colitis
• Dizurija
• Dysmenorrhea, unspecified
• Cholelithiasis
• An ulcer of the esophagus
• Duodenal ulcer
• Gastric ulcer

Farmakodinamika

Myotropic antispasmodic. It lowers the tone of smooth muscles of internal organs, reduces their locomotor activity, dilates blood vessels. No effect on the autonomic nervous system, It does not penetrate the CNS. Due to a direct effect on the smooth muscles, It can be used as spasmolytic in cases, when contraindicated drugs from the group of anticholinergics (glaucoma, prostatauxe). The on / in the beginning of the effect of the introduction of – through 2-4 m, maximal effect develops after 30 m.

Pharmacokinetics

In oralynom accept absorption – high, period poluabsorbtsii – 12 m. Bioavailability – 100%.

Application

Prevention and treatment of functional status and pain, induced smooth muscle spasm: počečnaâ how, pyelitis, spasms of the ureter; želčnaâ how, gipermotornaya biliary dyskinesia and gall bladder, cholecystitis; kišečnaâ how; spastic constipation, spasticheskiy colitis, proctitis, tenesmus; pilorospazm. Peptic ulcer and 12 duodenal ulcer in the acute phase (in the complex therapy). Pain in peripheral arterial spasm (endartyeriit), cerebrovascular, coronary artery. Algomenorrhea, risk of miscarriage and premature birth; spasm of the cervix during labor, disclosure prolonged throat, afterpains. To carry out some instrumental studies, holetsistografii.

Dosage regimen

Adults inside appoint 40-80 mg 3 times / day; / m, n / a – by 40-80 mg 1-3 times / day. For relief of hepatic and renal colic is introduced into / in slowly 40-80 mg. If peripheral vascular spasm drug can be administered intra-. Children under 6 years prescribed in a single dose 10-20 mg; 6-12 years – 20 mg; multiplicity of purposes 1-2 times / day.

Side effects

Dizziness, heartbeat, feeling the heat, Sweating. The on / in the introduction hypotension, collapse, OF блокада, Arrhythmia, depression of the respiratory center.

Contraindications

Hypersensitivity, glaucoma, prostate adenoma. Carefully – patients with severe coronary atherosclerosis, Pregnancy.

Cooperation

Reduces antiparkinson effect of levodopa.

Cautions

In the treatment of gastric ulcer and 12 duodenal ulcer is used in combination with other anti-ulcer agents.