RYNONORM

Active material: Ksilometazolin
When ATH: R01AA07
CCF: Vasoconstrictor drugs for local application in an ENT-practice
ICD-10 codes (testimony): H66, J00, J01, J30.1, J30.3, J32, Z51.4
When CSF: 24.05.01
Manufacturer: ratiopharm GmbH (Germany)

Pharmaceutical form, composition and packaging

◊ Spray nasal dose for children 0.05% as a clear, colorless solution.

Excipients: citric acid monohydrate, sodium citrate dihydrate, glycerol 85%, water d / and.

10 ml – vials of dark glass (1) with a metering device – packs cardboard.

◊ Spray nazalynыy dozirovannыy 0.1% as a clear, colorless solution.

Excipients: citric acid monohydrate, sodium citrate dihydrate, glycerol 85%, water d / and.

10 ml – vials of dark glass (1) with a metering device – packs cardboard.

Pharmacological action

Alpha-adrenomimetik for local application in ENT practice.

The local application of xylometazoline narrowing arteriol, reduces redness and swelling of the mucous membranes of the nasopharynx and reduce the discharge of secretions. Clear local effect of the drug is detected within a few minutes and lasts for a few hours (to 6-8 no), manifesting itself in restoring patency of the nasal passages, the openings of the sinuses and eustachian tubes. Air flotation recovery of nasopharynx improves patient and reduces the risk of possible complications, caused by the stagnation of mucous secretion.

Pharmacokinetics

When used topically ksilometazolin little rats, Therefore, the concentration in plasma is very small (analytically not defined).

Testimony

Rinonorm is used as a symptomatic therapy under the following diseases and conditions:

-acute viral or bacterial rhinitis;

- Acute allergic rhinitis;

-acute sinusitis or exacerbation of chronic sinusitis;

-acute otitis media (to reduce swelling of the mucous membrane of the eustachian tube);

-preparing the patient for diagnostic procedures in the bow moves.

Dosage regimen

Adults and children over 10 years appointed Rinonorm nasal spray 0.1% by 1 dose (1 pushing the piston device) in each of the bow no more 3 time / day.

Children aged 2 to 10 years Rinonorm appoint nazalny sprays for children 0.05% by 1 dose (1 pushing the piston device) in each of the bow no more 3 time / day.

The maximum you can apply no more than 7 time / day. The interval between the introduction of the drug should not be less than 6 no.

The amount of fluid, incoming in the bow of the patient (1 dose), is 0.14 ml.

In order to avoid complications in the form of a resumption of the symptoms of the disease duration of continuous use of the drug should not exceed 7 days.

Before using the drug should release the nasal passages from secretions. At the time of the introduction of the drug should make an easy breath through nose.

Side effect

Local reactions: stinging sensation and dryness of the mucous membrane of the nasal cavity; rarely – irritation of the mucous membranes of the nose, the oral cavity and larynx.

CNS: rarely – headache; rarely (< 1/10000) – insomnia, hypererethism.

Cardio-vascular system: rarely (< 1/10000) – arrhythmia, increase in HELL.

Other: rarely – nausea; rarely (< 1/10000) – skin reactions.

Contraindications

-atrophic (dry) rhinitis;

- Zakrыtougolynaya glaucoma;

— State after gipofizektomii;

— the simultaneous admission of MAO inhibitors and tricyclic antidepressants;

- Children up to age 2 years (for spray for kids);

- Children under the age of 10 years (for spray for adults);

-hypersensitivity to ksilometazolinu or other components of the drug.

FROM caution the drug should be used in hypertension, heavy heart disease, gipertireoze, diabetes and patients, host bromocriptine.

Pregnancy and lactation

The drug should not be taken during pregnancy.

Precautions should use the drug during breastfeeding.

Cautions

Effects on ability to drive vehicles and management mechanisms

Impact on the ability of driving transport and the management of machines and mechanisms is not marked.

Overdose

Symptoms: in rare cases of overdoses, occur mainly in children, arrhythmia may occur, increased blood pressure, in some cases – loss of consciousness.

Treatment: shown symptomatic therapy under the supervision. In serious cases can be applied selective Alpha-adrenoreceptor antagonists to reduce AD, as well as intubation and IVL. Sossoudossoujiwate drugs contraindicated. If you accidentally receiving moderate or large amounts of the drug inside, should take activated charcoal and laxative (eg, sodium sulfate), gastric lavage.

Drug Interactions

Simultaneous reception of three- or tetraciklicheskih antidepressants may increase systemic effects ksilometazolina.

While receiving the drug with MAO inhibitors can risk ad.

Conditions of supply of pharmacies

The drug is resolved to application as an agent Valium holidays.

Conditions and terms

The drug should be stored out of reach of children at or above 25 ° C. Shelf life – 3 year, After opening the bottle – 1 year.