Rinofluimucil

Active material: Acetylcysteine, Tuamynoheptan
When ATH: R01AB08
CCF: The drug with mucolytic and vasoconstrictor action for local application in an ENT-practice
ICD-10 codes (testimony): J00, J01, J30.0, J31, J32
When CSF: 24.08.02
Manufacturer: ZAMBON S.p.A. (Italy)

Pharmaceutical form, composition and packaging

◊ Spray nazalynыy a substantially colorless transparent liquid with a characteristic odor of sulfur slightly minty.

Excipients: benzalkonium chloride, gipromelloza, disodium эdetat, sodium dihydrogen, sodium hydrogen phosphate dodecahydrate, dithiothreitol, sorbitol 70%, mint flavor, ethanol 96%, Sodium hydroxide, Purified water.

10 ml – vials of dark glass (1) complete with nozzle spray – packs cardboard.

Pharmacological action

The drug with mucolytic and vasoconstrictor action for use in ENT practice.

Acetylcysteine ​​thins mucus and purulent mucus by breaking disulfide bonds mucus glycoproteins. Also it has anti-inflammatory (due to inhibition of leukocyte chemotaxis) and antioxidant effects.

Tuaminoheptane sulfate – simpatomimyetichyeskii vital, providing local application vasoconstrictor effect. Eliminates edema and hyperemia of the nasal mucosa.

Pharmacokinetics

When applied topically in the recommended doses, the drug is not absorbed.

Testimony

- Acute and sub-acute rhinitis with dense is purulent-mucous secretion;

- Chronic rhinitis;

- Vasomotor rhinitis;

- Sinusitis.

Dosage regimen

The drug is administered to the nasal cavity in the form of an aerosol spray using a special.

Adults administered by 2 dose aerosol (2 clicking on the valve) in each nostril 3-4 times / day.

Babies the drug is prescribed for 1 dose aerosol (1 pressing the valve) in each nostril 3-4 times / day. Duration of therapy should not exceed 7 days.

Do not exceed the recommended dose and treatment without consulting your doctor.

Terms of use of the drug

1.Remove the cap from the bottle with a solution.

2. Remove the cap from the sprayer.

3. Remove the lid from the sprayer.

4. Activate by pressing the sprayer.

Side effect

Cardio-vascular system: heartbeat, tachycardia, arterial hypertension.

CNS: rarely – excitation, tremor.

Local reactions: dryness of the nasal mucosa, mouth and pharynx.

Other: rarely – allergic reactions, urinary retention, inflammation of the sebaceous glands.

With prolonged use of vasoconstrictors may change the normal function of the nasal mucosa and sinuses, and the development of addiction to the drug.

Contraindications

- Zakrыtougolynaya glaucoma;

- Thyrotoxicosis;

- Simultaneous use of MAO inhibitors and the period up to 14 days after their cancellation;

- Simultaneous use of tricyclic antidepressants and the period up to 14 days after their cancellation;

- Hypersensitivity to the drug.

FROM caution prescribe the drug to children under 3 years, patients with bronchial asthma, hypertension, III-IV angina functional class, frequent arrythmia (Treatment should be under medical supervision).

Pregnancy and lactation

Use of the drug during pregnancy and lactation is possible only in cases, when the intended benefits to the mother outweighs the potential risk to the fetus and child.

Cautions

The product is only intended for intranasal administration.

Effects on ability to drive vehicles and management mechanisms

The drug does not affect the patients' ability to drive vehicles and other mechanisms.

Overdose

Symptoms: may develop systemic side effects, caused part of the drug tuaminogeptanom (tachycardia, tremor, anxiety, increased blood pressure, adaptation).

Treatment: if necessary, symptomatic therapy.

Drug Interactions

In a joint application Rinofluimutsil^® MAO inhibitors and tricyclic antidepressants increases the risk of systemic side effects, due tuaminogeptanom (tk. These drugs potentiate the action of sympathomimetic drugs).

In an application Rinofluimutsil^® may weaken the effect of antihypertensive drugs.

Conditions of supply of pharmacies

The drug is resolved to application as an agent Valium holidays.

Conditions and terms

The drug should be stored out of reach of children at temperature from 15 ° to 25 ° C. Shelf life – 2.5 year.

After opening the bottle contents can be used for 20 days.