Panzinorm FORTE 20 000
Active material: Pancreatin
When ATH: A09AA02
CCF: The enzyme preparation
ICD-10 codes (testimony): E84, K30, K83.1, K86.1, K86.8, K90.3, K91.2, K91.5, Z51.4
When CSF: 11.05
Manufacturer: KRKA d.d. (Slovenia)
Pharmaceutical form, composition and packaging
◊ Pills, enteric coated white or light gray, smooth, round, lenticular, flavored.
| 1 tab. | |
| Pancreatin enzyme activity with minimal: | |
| lipase | 20 000 ED Ph.Eur. |
| amilazы | 12 000 ED Ph.Eur. |
| proteases | 900 ED Ph.Eur. |
Excipients: lactose monohydrate, microcrystalline cellulose, krospovydon, colloidal silicon dioxide, magnesium stearate, gipromelloza, Titanium dioxide (E171), talc, vanillin, bergamot, macrogol 6000, carmellose sodium.
10 PC. – blisters (1) – packs cardboard.
10 PC. – blisters (3) – packs cardboard.
10 PC. – blisters (10) – packs cardboard.
Pharmacological action
The enzyme preparation. Compensates for lack of exocrine pancreatic function. Included in the pancreatin enzymes lipase, amylase and protease facilitate digestion of fats, carbohydrates and proteins, which contributes to a more complete absorption in the gut.
Pharmacokinetics
The data on the pharmacokinetics Panzinorm® forte 20 000 not provided.
Testimony
- Lack of exocrine pancreatic function (incl. chronic pancreatitis, mukovystsydoz);
- Chronic inflammatory and degenerative diseases of the stomach, bowel, liver, gallbladder; state after resection or irradiation of these bodies, accompanied by a violation of the digestion of food, meteorizmom, diarrhea (in a combination therapy);
- To improve food digestion in patients with normal function of the gastrointestinal tract in the case of errors in the diet;
- Preparation for X-ray and ultrasound of the abdominal cavity.
Dosage regimen
The dose is determined individually, depending on the degree of digestive disorders.
Adults usually prescribed for 1 tab. mealtime.
The dosage regimen for children determined by the clinical situation.
The duration of treatment with disorders of the digestive process due to errors in the diet It may vary from one reception to several days; at permanent replacement therapy – up to several months or years.
Tablets should be taken with liquid, drinking plenty of fluids.
Side effect
From the digestive system: rarely – diarrhea. In cystic fibrosis in the case of excess of the required dose of pancreatin may develop strictures (fibrous colonopathy) in the ileocecal region and in the ascending colon.
From the urinary system: long-term use at high doses may develop hyperuricosuria, hyperuricemia.
Other: allergic reactions.
Contraindications
- Acute pancreatitis;
- Exacerbation of chronic pancreatitis;
- Hypersensitivity to the drug or to pork.
The drug should not be given to children under 15 years with concomitant cystic fibrosis.
Pregnancy and lactation
The safety of the drug Panzinorm® forte 20 000 Pregnancy and lactation (breast-feeding) not installed.
Cautions
In cystic fibrosis dose should be adequate number of enzymes, required for fat absorption in terms of quality and quantity of food consumed.
Overdose
Symptoms: giperurikozurija, hyperuricemia; children – constipation.
Treatment: you need to stop the drug and Symptomatic treatment.
Drug Interactions
While the use of pancreatin a decline absorption of iron and folic acid.
The simultaneous use of histamine H2-receptors, proton pump inhibitors or antacids may reduce the effectiveness of pancreatin.
Conditions of supply of pharmacies
The drug is resolved to application as an agent Valium holidays.
Conditions and terms
The drug should be stored in a dry place at temperatures no higher than 25 ° C. Shelf life – 3 year.
