OFLOMELID

Active material: Methyluracil, Lidokain, Ofloxacin
When ATH: D06BX
CCF: With antibacterial drug, Valium and improves tissue regeneration effect for external use
ICD-10 codes (testimony): I83.2, L89, T30, T79.3
When CSF: 06.17.02.02
Manufacturer: Synthesis of (Russia)

Pharmaceutical form, composition and packaging

Ointment for external application white or nearly white.

Excipients: metilparagidroksiʙenzoat (nipagin or methyl paraben), propilparagidroksibenzoat (nipazol or propyl), propylene glycol, macrogol 1500 (low molecular weight polyethylene glycol 1500 and polyethylene 1500), macrogol 400 (low molecular weight polyethylene glycol 400 and polyethylene 400).

30 g – aluminum tuba (1) – packs cardboard.

Pharmacological action

Combined preparation, It has antimicrobial, anti-inflammatory, mestnoanesteziruyuschee, regenerative effect.

Ofloxacin – antimicrobial agent is a broad spectrum fluoroquinolone. It has a bactericidal effect by blocking DNA gyrase in bacterial cells. Active against gram-negative and gram-positive organisms.

Methyluracil – stimulator of tissue repair. It has anabolic activity. Accelerates cell regeneration in wounds, accelerating the growth and maturation of the granulation tissue and epithelialization.

Lidocaine has a local anesthetic effect due to the blockade of sodium channels, which prevents generation of impulses in endings of sensory neurons, and the conduction of impulses along nerve fibers. For external use dilates blood vessels, does not have any irritant action.

Water-soluble ointment base is a mixture of polyethylene oxide having a molecular weight 400 and 1500, provides a dehydrating effect on the fabric, in 20 times superior in strength of action 10% sodium chloride solution.

Pharmacokinetics

Data on the pharmacokinetics Oflomelid^® not provided.

Testimony

Infected sores of various localization and etiology in the first (pyonecrotic) phase of wound healing process, incl. accompanied by severe pain:

- Infected burns II-IV degree;

- Bedsores;

- Sores;

- Postoperative and post-traumatic wounds and fistulae;

- Wounds after opening the abscess, phlegmons, after surgical treatment of an abscessed furuncles, carbuncles, gidradenity, festering atheroma, Lipoma.

Dosage regimen

The drug is used topically, 1 times / day for 1-2 weeks. The maximum daily dose should not exceed 100 g ointment. The duration of treatment depends on the dynamics of the cleansing of wounds from purulent exudate and terms of relief of the inflammatory process.

After standard work wounds and burns ointment is applied directly on the wound surface with a thin layer (then impose a sterile gauze bandage) or gauze bandage, followed by application on the lesion.

Tampons, impregnated with ointment, loosely fill oral purulent wounds after debridement, turundy gauze and ointment is introduced into the fistulous passages.

At treatment of infected burns The drug is used daily or 2-3 times a week, depending on the amount of purulent discharge.

Side effect

Maybe: allergic reactions.

Contraindications

- Pregnancy;

- Lactation;

- Childhood and adolescence up 18 years;

- Hypersensitivity to the drug.

Pregnancy and lactation

The drug is contraindicated in pregnancy and lactation (breast-feeding).

Cautions

–

Overdose

Data on drug overdose Oflomelid^® not provided.

Drug Interactions

There were no cases of interaction with drugs, which would lead to a decrease in the efficacy and safety of the drugs.

Conditions of supply of pharmacies

The drug is released under the prescription.

Conditions and terms

The drug should be stored out of reach of children, dark place at a temperature between 15 ° C and 25 ° C. Shelf life – 2 year.