NESOPIN

Active material: Oksimetazolin
When ATH: R01AA05
CCF: Vasoconstrictor drugs for local application in an ENT-practice
ICD-10 codes (testimony): H68, J00, J01, J30.1, J30.3, J31, J32
When CSF: 24.05.01
Manufacturer: Synthesis of (Russia)

Pharmaceutical form, composition and packaging

◊ Spray nazalynыy 0.05% in the form of colorless or yellowish brown color, transparent or opalesciruûŝej fluid.

Excipients: menthol, eucalyptus oil, disodium эdetat, disodium dodekagidrat phosphate, sodium dihydrogen phosphate dihydrate, propylene glycol, benzyl alcohol, water d / and (to 1 ml).

10 ml – plastic bottles (1) with spray nozzle – packs cardboard.
20 ml – plastic bottles (1) with spray nozzle – packs cardboard.

Pharmacological action

Alpha-adrenomimetik for local use. It has a vasoconstrictor effect. In intra reduces swelling of mucous membrane upper divisions respiratory tract.

The effect is manifested through 15 minutes after application and lasts for 8-12 no.

Pharmacokinetics

The farmakokinetike drug Nesopin^® not provided.

Testimony

- Rhinitis (allergic and infectious-inflammatory etiology);

- Sinusitis;

- Evstahiit;

-hay fever.

Dosage regimen

Adults and children over 12 years administered intranasally 2-3 injection in each of the bow at intervals 10-12 no.
Children from 6 to 12 years – by 1 injection in each of the bow at intervals 10-12 no.

Side effect

Local reactions: passing the dryness and burning of mucous membrane of the nasal cavity, dry mouth and throat, chikhaniye. With prolonged use – taxifilaksija, reactive hyperemia of the mucosa and atrophy of the nasal mucosa.

Systemic reactions: increased blood pressure, increased anxiety, nausea, dizziness, headache, insomnia, heartbeat, sleep disorders.

Contraindications

- Atrophic rhinitis;

- Pregnancy;

- Lactation (breast-feeding);

- Children up to age 6 years;

- Hypersensitivity to the drug.

FROM caution should designate product in chronic heart failure, Arrhythmia, expression of atherosclerosis, hypertension, thyrotoxicosis, diabetes, chronic renal failure, angle-closure glaucoma.

Pregnancy and lactation

The drug is contraindicated in pregnancy and during breastfeeding.

Cautions

In the recommended dosage without consultation with a physician, medication can be used no more than 3 days.

Avoid contact with the eyes.

Effects on ability to drive vehicles and management mechanisms

The drug affects vision (In case of eye), the decline in the rate of reaction. The dosages, exceeding recommended, It may affect the ability to drive a vehicle or equipment.

Overdose

Symptoms: tachycardia, increased blood pressure, CNS depression.

Treatment: symptomatic therapy.

Drug Interactions

Slows down the absorption of local anaesthetic drugs, extends the effect of.

Co-administration of other vasoconstrictor drugs increases the risk of side effects.

When concomitant administration of MAO inhibitors and tricyclic antidepressants may increase blood pressure.

Conditions of supply of pharmacies

The drug is resolved to application as an agent Valium holidays.

Conditions and terms

The drug should be stored in a dark and inaccessible to children at temperature from 15 ° to 25 ° C. Shelf life – 2 year.