Active material: Etiltiobenzimidazola hydrobromide
When ATH: A13A
CCF: The drug is a tonic and adaptogenic action
ICD-10 codes (testimony): F07, F07.2, F48.0, G00, G04, I69, T90, Z54, Z73.0, Z73.3
When CSF: 02.14
Manufacturer: Antiviral NPO ZAO (Russia)
Capsules hard gelatin, №3, white housing, cap yellow; содержимое капсул – смесь порошка и гранул белого или белого с кремоватым оттенком цвета.
| 1 caps. | |
| etiltiobenzimidazola hydrobromide (monohydrate) | 50 mg |
Excipients: giproloza, colloidal silicon dioxide, lactose, magnesium stearate.
Composition of hard gelatin capsules: gelatin, colorant sunset yellow (E110), quinoline yellow dye (E104), metilparagidroksiʙenzoat, propilparagidroksibenzoat, Titanium dioxide (E171), water.
10 PC. – упаковки ячейковые контурные (2) – пачки картонные.
10 PC. – упаковки ячейковые контурные (5) – пачки картонные.
100 PC. – банки полимерные (1) – пачки картонные.
Capsules hard gelatin, №2, white housing, orange cap; содержимое капсул – смесь порошка и гранул белого или белого с кремоватым оттенком цвета.
| 1 caps. | |
| etiltiobenzimidazola hydrobromide (monohydrate) | 125 mg |
Excipients: giproloza, colloidal silicon dioxide, lactose, magnesium stearate.
Composition of hard gelatin capsules: gelatin, colorant sunset yellow (E110), metilparagidroksiʙenzoat, propilparagidroksibenzoat, Titanium dioxide (E171), water.
10 PC. – упаковки ячейковые контурные (2) – пачки картонные.
10 PC. – упаковки ячейковые контурные (5) – пачки картонные.
100 PC. – банки полимерные (1) – пачки картонные.
Capsules hard gelatin, №3, white housing, cap dark orange; содержимое капсул – смесь порошка и гранул белого или белого с кремоватым оттенком цвета.
| 1 caps. | |
| etiltiobenzimidazola hydrobromide (monohydrate) | 250 mg |
Excipients: giproloza, colloidal silicon dioxide, lactose, magnesium stearate.
Composition of hard gelatin capsules: gelatin, carmine dye Ponceau 4R (E124), colorant sunset yellow (E110), metilparagidroksiʙenzoat, propilparagidroksibenzoat, Titanium dioxide (E171), water.
10 PC. – упаковки ячейковые контурные (2) – пачки картонные.
10 PC. – упаковки ячейковые контурные (5) – пачки картонные.
100 PC. – банки полимерные (1) – пачки картонные.
Preparation with adaptogenic action. It has nootropnoy, antihypoxic, antioxidant and immunomodulatory activity, improves tissue regeneration.
The mechanism of action is the activation of RNA synthesis, then proteins, incl. enzyme and related to the immune system. The activation of the synthesis of enzymes of gluconeogenesis, that provide utilization of lactate (factor a, limiting operation) и ресинтез углеводов – источника энергии при интенсивных нагрузках, which leads to increased physical performance. Increased synthesis of mitochondrial enzymes and structural proteins of the mitochondria provides increased energy production and maintaining a high degree of coupling of oxidation and phosphorylation. Continued high levels of ATP synthesis deficiency of oxygen helps expressed antihypoxic and antiischemic activity.
It increases synthesis of antioxidant enzymes and has a pronounced antioxidant activity. Повышает устойчивость организма к воздействию экстремальных факторов – физической нагрузке, stress, hypoxia, Hyperthermia. Improves performance during exercise.
It possesses strong action antiastenicheskim, accelerates recovery from extreme impacts.
The maximum effect is achieved after 1-2 h after dosing, duration of action 4-6 no. Against the background of course taking effect usually grows in the first 3-5 days, then steadily maintained at the current level.
After ingestion well absorbed from the gastrointestinal tract. After a single dose is found in the blood 30 m. With long-term continuous administration of kursovom, especially in high doses, there may be a tendency to accumulation of the drug with an increase in its concentration in the blood to 10-12 Day use.
Extensively metabolized in the liver.
The drug is prescribed inside, after meal.
Adults appoint 250 mg 2 times / day. If necessary, the daily dose is increased to 750 mg (500 mg in the morning and 250 мг – после обеда), and patients with a body weight above 80 кг – до 1 g (by 500 mg 2 times / day).
A course of treatment - 5 days with 2 day intervals between them in order to avoid accumulation of the drug. The number of courses depends on the effect and averages 2-3 (less often 1 or 4-6) rates.
To improve performance in extreme conditions take medication for 40-60 minutes before the upcoming activity at a dose of 500-750 mg. If you continue to work through the readmission produce 68 h dose 250 mg. The maximum daily dose - 1.5 g, а в последующие сутки – 1 g.
To maintaining a high level of efficiency for a long time (few weeks) and for activation of adaptive processes the drug is prescribed under the scheme: 5-day course of a 2-day intervals at a dose 250 mg 2 times / day.
From the digestive system: discomfort in the stomach and liver; rarely - nausea, vomiting.
Allergic reactions: facial flushing, rhinitis.
CNS: headache.
Use of the drug Metaprot® contraindicated during pregnancy and lactation.
The drug should not be taken in the evening (possible violation of falling asleep).
When adverse reactions necessary to reduce the dose or stop taking the drug.
During treatment with the recommended diet, rich in carbohydrates.
Symptoms: hypererethism, sleep at night.
Treatment: gastric lavage, administration of activated charcoal, при необходимости – симптоматическая терапия.
Inhibitors of microsomal liver enzymes CYP1A2, CYP2C9, CYP2D6, CYP3A4 (eg, cimetidine) can increase the concentration of drug in the blood.
Metaprot® It enhances the beneficial effects of metabolic drugs (incl. inozina (cm. instructions Groprinosin), nootropics (incl. piracetam), antihypoxic funds (incl. trimetazidine), potassium and magnesium asparaginata, glutamic acid, vitamins (incl. a-токоферол), and antianginal drugs (nitrates, beta-blockers).
The drug is released under the prescription.
List B. The drug should be stored in a dry, protected from light, inaccessible to children at temperature not exceeding 25 ° C. Shelf life - 3 year.
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