Active material: Magnesium lactate, Pyridoxine
When ATH: A12CC30
CCF: Preparation, filling shortage of magnesium in the body
ICD-10 codes (testimony): E61.2
When CSF: 01.11.02.02.01
Manufacturer: Pharmstandard-UfaVITA JSC (Russia)
◊ Pills, coated white or nearly white, round, lenticular.
| 1 tab. | |
| Magnesium lactate | 470 mg |
| pyridoxine hydrochloride | 5 mg |
Excipients: sucrose, povidone (Kollidon 30), коллидон SR (polyvinyl, povidone, sodium lauryl, silicon dioxide), magnesium stearate, carmellose sodium (sodium carboxymethylcellulose), talc.
The composition of the shell: sucrose, kaolin (White clay), gelatin, acacia (gummiaraʙik), beeswax white, carnauba wax, talc, Titanium dioxide.
10 PC. – упаковки ячейковые контурные (3) – пачки картонные.
10 PC. – упаковки ячейковые контурные (5) – пачки картонные.
60 PC. – банки полимерные (1) – пачки картонные.
90 PC. – банки полимерные (1) – пачки картонные.
Preparation, filling shortage of magnesium.
Magnesium is a vital element, which is found in all tissues of the body and is necessary for normal functioning of cells. Participates in many metabolic reactions, in the regulation of nerve impulse transmission and muscle contraction, has antispasmodic, antiarrhythmic and antiplatelet effect.
The body gets magnesium with food. Lack of magnesium in the body can be observed in eating disorders (diet) or by increasing the demand for magnesium (during increased physical and mental stress, stress, pregnancy, diuretics).
Pyridoxine (vitamin B6) It participates in many metabolic processes, in the regulation of metabolism of the nervous system. Improves absorption of magnesium from the gastrointestinal tract and its penetration into cells.
The magnesium content of the serum 12 to 17 mg / l (0.5-0.7 mmol / l) evidence of moderate magnesium deficiency; below 12 mg / l (0.5 mmol / l) – о тяжелом дефиците магния.
Absorption
After receiving the drug inside the magnesium absorption from the gastrointestinal tract is 50%.
Deduction
Report mostly kidneys. In the kidney after glomerular filtration 70% magnesium present in the plasma, its reabsorption in the renal tubules is 95-97%.
- Mounted magnesium deficiency, isolated or associated with other deficiency states.
Adults It is encouraged to nominate 6-8 tab. / day. Children over 6 years (weighing more than 20 kg) – 4-6 tab. / day. The daily dose should be divided into 2-3 admission.
Treatment should be discontinued after the normalization of the concentration of magnesium in the blood.
The drug should be taken with food, with a glass of water.
From the digestive system: stomach ache, constipation, nausea, vomiting, flatulence.
Allergic reactions: allergic reactions.
- Severe renal insufficiency (CC less than 30 ml / min);
- Phenylketonuria;
- Children up to age 6 years;
- Hypersensitivity to the drug.
FROM caution the drug should be used in patients with moderate renal insufficiency, tk. there is a risk of gipermagniemii.
Clinical experience has not revealed foetotoxic or teratogenic effect of the drug.
Magnelis® B6 can be used during pregnancy only on prescription.
Magnesium gets excreted in breast milk. Should be avoided during lactation and breastfeeding.
If necessary, use of the drug in patients with diabetes should be aware, Tablets that contain sucrose as the excipient.
In the case of concomitant calcium deficiency, magnesium deficiency should be addressed before you start taking calcium supplements.
In normal renal function receiving magnesium inside does not cause toxic reactions. Magnesium poisoning can occur in renal failure. Toxic effects are mainly dependent on the magnesium content in blood serum.
Symptoms: drop in blood pressure, nausea, vomiting, slowing of reflexes, anurija, respiratory depression, coma, cardiac arrest.
Treatment: regidratatsiya, diurez. When kidney failure need hemodialysis or peritoneal dialysis.
With simultaneous use of drugs, containing phosphate or calcium salt, perhaps a significant reduction in the absorption of magnesium from the gastrointestinal tract.
Preparations magnesium reduce absorption of tetracycline, it is recommended to share their drug 3-hour intervals.
Magnesium reduces the effect of oral thrombolytic agents, reduces the absorption of iron.
Vitamin B6 inhibits the activity of levodopa.
The drug is resolved to application as an agent Valium holidays.
The drug should be stored out of reach of children, dark place at a temperature no higher than 25 ° C. Shelf life - 2 year.
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