Active material: Magnesium lactate, Pyridoxine
When ATH: A11JB
CCF: Preparation, filling shortage of magnesium in the body
ICD-10 codes (testimony): E61.2
When CSF:
Manufacturer: SANOFI-AVENTIS France (France)

Pharmaceutical form, composition and packaging

Pills, coated white, Oval, lenticular, with a smooth shiny surface.

1 tab.
Magnesium lactate dihydrate470 mg,
Mg content equivalent2+48 mg
pyridoxine hydrochloride5 mg

Excipients: sucrose, kaolin tyazhelыy, acacia gum, carboxypolymethylene 934, talc (magnesium hydrosilicate), magnesium stearate.

The composition of the shell: acacia gum, sucrose, Titanium dioxide, talc (magnesium hydrosilicate), carnauba wax (powder).

10 PC. – blisters (5) – packs cardboard.

Oral solution clear, Brown color, with the smell of caramel.

1 amp.
Magnesium lactate dihydrate186 mg
Magnesium pidolate936 mg,
which is equivalent to the total content of Mg2+100 mg
pyridoxine hydrochloride10 mg

Excipients: sodium bisulfite, sodium saccharin, cherry caramel flavor, Purified water.

10 ml – double-ended vials of dark glass (10) – inserts made of cardboard (1) – packs cardboard.


Pharmacological action

The preparation of magnesium. Magnesium is a vital element, which is found in all tissues of the body and is necessary for normal functioning of cells, involved in most metabolic reactions. In particular, participates in the regulation of nerve impulse transmission and muscle contraction.

The body gets magnesium with food. Lack of magnesium in the body can be observed in eating disorders (incl. subject to reduction diets) or by increasing the demand for magnesium (during increased physical and mental stress, stress, pregnancy, diuretics).

Pyridoxine (vitamin B6) It participates in many metabolic processes, in the regulation of metabolism of the nervous system. Improves absorption of magnesium from the gastrointestinal tract and its penetration into cells.

The magnesium content of the serum 12 to 17 mg / l (0.5-0.7 mmol / l) He speaks of moderate magnesium deficiency; below 12 mg / l (0.5 mmol / l) It indicates severe deficiency of magnesium.



Absorption and distribution

The absorption of magnesium from the gastrointestinal tract is 50% received an oral dose of. The magnesium body is distributed mainly in the intracellular space (about 99%), of which approximately 2/3 distributed in the bone, and the third is in smooth and striated muscle tissue.


Magnesium is excreted mainly by the kidneys. Magnesium, present in the urine, averages 1/3 received magnesium.



- Mounted magnesium deficiency, isolated or associated with other deficiency states, accompanied by symptoms such as increased irritability, minor sleep disturbances, gastrointestinal cramps or heart palpitations, fatigue, pain and muscle spasms, prickle.


Dosage regimen

Pills, coated: adult Recommend designate, 6-8 tab. / day, older children 6 years (weighing more than 20 kg) – 4-6 tab. / day. The daily dose should be divided into 2-3 admission. Tablets are taken with meals, with a glass of water.

Oral solution: adult are encouraged to nominate 3-4 ampoules / day, older children 1 year (weighing more than 10 kg) – 1-4 ampoules / day. The daily dose should be divided into 2-3 admission. A solution of the vials are dissolved in 1/2 a glass of water for receiving 2-3 times / day with meals.

The average duration of treatment is 1 month.

Treatment should be discontinued after the normalization of magnesium in the blood.

Samonadlamyvayuschiesya vials Magne B6® does not require the use of nail files. To open the ampoule, should take her tip, previously covered it with a cloth and break off abruptly.


Side effect

From the digestive system: rarely – stomach ache, nausea, vomiting, flatulence, constipation.

Other: perhaps – allergic reaction to the drug.



- Severe renal insufficiency (CC < 30 ml / min);

- Phenylketonuria;

- Children up to age 6 years (Pill);

- Children up to age 1 year (for a solution);

- Fructose intolerance;

- A syndrome of impaired absorption of glucose or galactose;

- Lack of sucrase-isomaltase;

- Hypersensitivity to the drug.

FROM caution prescribe the drug for renal insufficiency moderately, tk. there is a risk of gipermagniemii.


Pregnancy and lactation

Application Magne B6® when pregnancy is possible only on the testimony and under medical supervision.

Should be avoided during lactation (breast-feeding). Magnesium is excreted in breast milk.



With concomitant calcium deficiency magnesium deficiency in the body must be removed before you start taking calcium supplements.

With frequent use of laxatives, alcohol consumption, under intense physical and mental stress increases the need for magnesium and increases the risk of magnesium deficiency in the body.

In a joint application of tetracycline and Magne B6® should observe a 3-hour interval between doses of these drugs.

In applying the drug in patients with diabetes should be aware, tablets, coated, contain sucrose as the excipient.

It will be appreciated, that the oral solution contains sulfite, that can cause or exacerbate allergic and anaphylactic reactions in patients at risk.

The drug in tablet form is only for adults and children over 6 years. In young children, it is recommended to use the drug in the form of oral solution.

Effects on ability to drive vehicles and management mechanisms

The drug does not affect the ability to drive vehicles and other activities, require high concentration and speed of psychomotor reactions.



In normal renal function receiving magnesium inside does not cause toxic reactions. Magnesium poisoning can occur in renal failure. Toxic effects are mainly dependent on the magnesium content in blood serum.

Symptoms: decrease in blood pressure, nausea, vomiting, depression, slowing of reflexes, distortion of ECG, respiratory depression, coma, cardiac arrest and heart failure, anurichesky syndrome.

Treatment: regidratatsiya, diurez. When kidney failure need hemodialysis or peritoneal dialysis.


Drug Interactions

With simultaneous application of Magne B6® and preparations, salts containing calcium and phosphates, It can significantly reduce the absorption of magnesium from the gastrointestinal tract.

At simultaneous intake of magnesium reduces the absorption of tetracycline.

In a joint application of magnesium reduces the effect of oral thrombolytic agents, reduces the absorption of iron.

Pyridoxine, which is part of Magne B6®, inhibits the activity of levodopa.


Conditions of supply of pharmacies

The drug is resolved to application as an agent Valium holidays.


Conditions and terms

Pills, coated, It should be stored in a dry, dark place at a temperature no higher than 25 ° C. Shelf life – 2 year.

Oral solution should be stored in a dark place at a temperature no higher than 25 ° C. Shelf life – 3 year.

The drug should be stored out of reach of children.

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