KORILIP

Active material: Kokarboksilazu hydrochloride, Riboflavin, Thioctic acid
When ATH: A11JC
CCF: The drug is a tonic effect
ICD-10 codes (testimony): P92.3, Z54, Z73.0, Z73.3
When CSF: 16.07.01
Manufacturer: ALTFARM Ltd. (Russia)

Pharmaceutical form, composition and packaging

Rectal Suppositories yellow with possible interspersed orange-yellow,torpedo-shaped.

Excipients: cocoa butter or hard fat.

5 PC. – packings Valium planimetric (2) – packs cardboard.

Pharmacological action

The drug is a tonic effect. Combined preparation, the effect of which is determined by the effects, in its composition of vitamins and coenzymes, as well as the synergies between.

Kokarboksilazu hydrochloride (coenzyme) катализирует карбоксилирование и декарбоксилирование a-кетокислот, involved in the processes of carbohydrate metabolism, through participation in the pentose cycle indirectly promotes the synthesis of nucleic acids, proteins, lipids. Activates tissue metabolism. The drug is used to correct the metabolic acidosis, cell hypoxia, Other metabolic disorders, with insufficient liver function, kidney, Cardiovascular, chronic intoxications.

Riboflavin (vitamin B₂) flavinproteinov as a coenzyme is involved in regulating the redox reactions, and in the processes of carbohydrate, protein and fat metabolism; It plays an important role in the synthesis of hemoglobin and maintenance of normal visual functions of the eye, state mucocutaneous.

Lipoic acid is involved in the oxidative decarboxylation of pyruvic acid and α-keto acid, in the regulation of lipid and carbohydrate metabolism, It plays an important role in energy production in the body. Lipoic acid has a hepatoprotective action, improves the detoxifying function of the liver, protects against exo- and endotoxins.

Korilip improves tissue metabolism in various physiological and pathological conditions, requiring correction of substrates and cofactors.

Pharmacokinetics

The data on the pharmacokinetics Korilip not provided.

Testimony

As a monotherapy or as an addition to basic therapy in various pathological conditions in children, including:

- Chronic tissue hypoxia;

- Reduced immunity;

- Bacterial and viral infections;

- Chronic somatic diseases;

- Chronic toxicity;

- State after serious illness;

- Malnutrition (gipotrofiя).

Periods of intense growth and the formation of the new features in the child, during intense physical and mental stress, in stressful situations.

As a tonic for the prevention during epidemics of infectious diseases.

Dosage regimen

The drug is used rectally. Freed from the package, enter the suppository into the anus (after prior bowel).

Newborns and infants appointed 1/2 suppository / day; children aged 1 Year to 6 years) – by 1 suppository / day; children aged 6 to 14 years – 1-2 suppository / day.

Duration of treatment – 10 days. The total duration of treatment – 3-4 course with an interval 20 days (3-4 Months).

Side effect

Allergic reactions: rarely – hives, itch, bronchospasm, dyspepsia.

When adverse reactions the patient should stop taking the drug and seek medical advice.

Contraindications

- Proctitis;

- Rectal bleeding;

- Hypersensitivity to the drug.

Cautions

The criteria for the duration of treatment, along with the clinical condition are cytochemical indicators of enzyme activity of peripheral blood leukocytes (glycerophosphate and succinate dehydrogenase).

Overdose

Data on drug overdose Korilip not provided.

Drug Interactions

Negative interactions were observed.

The drug can be used in combination therapy.

Conditions of supply of pharmacies

The drug is released under the prescription.

Conditions and terms

The drug should be stored out of reach of children, dark place at a temperature no higher than 9 ° C. Shelf life – 2 year.