Coldrex BRONCHO
Active material: Guaifenesin
When ATH: R05CA03
CCF: Expectorant medication
ICD-10 codes (testimony): J04, J06.9, J10, J20, R05
When CSF: 12.02.03
Manufacturer: GlaxoSmithKline Consumer Healthcare (Great Britain)
Pharmaceutical form, composition and packaging
◊ Syrup dark brown, Coupling, with the smell of licorice and anise.
| 5 ml | |
| guaifenesin | 100 mg |
Excipients: dextrose (solution), molasses, macrogol 300, dye (Kohler sugar easy), sodium cyclamate, glacial acetic acid, Sodium benzoate, flavoring liquorice anise 510877E, bitter red peppers, Acesulfame K, sodium metabisulfite, Xanthan Gum (Keltrol TF), star anise seed oil, levomenthol, Camphor racemic, water deionized.
100 ml – glass bottles (1) complete with a measured glass – packs cardboard.
160 ml – glass bottles (1) complete with a measured glass – packs cardboard.
Pharmacological action
Expectorant medication. It reduces surface tension and adhesion properties of sputum, that reduces its viscosity and facilitates the removal of the respiratory tract. The drug promotes the transition of non-productive cough in a productive.
Members of the drug syrup and glucose have emollient and enveloping effect on the mucous membranes of the pharynx.
The drug reduces the pain and irritation in the throat for colds and flu.
Pharmacokinetics
Guayfenezin rapidly absorbed from the digestive tract. Cmax achieved through 25-30 minutes after ingestion.
It penetrates tissue, containing acid mucopolysaccharides.
T1/2 is 0.5 – 1 no. Displays with sputum and urine in unchanged form and in the form of metabolites.
Testimony
Respiratory system diseases, accompanied by cough with formation of viscous sputum trudnootdelema, including:
-influenza;
— acute tracheitis;
is bronchitis different etiology;
— catarrh of the upper respiratory tract.
Dosage regimen
Adults (including elderly patients) and children over the age of 12 years drug administered in a single dose 200 mg (10 ml). Should infuse the syrup attached measuring cup to mark 10 ML and drink preparation. The single dose can be taken again every 2-3 no.
Children aged 3 to 12 years drug administered in a single dose 100 mg (5 ml). Should infuse the syrup attached measuring cup to mark 5 ML and drink preparation. The single dose can be taken again every 2-3 no.
Side effect
From the digestive system: sometimes – nausea, vomiting, stomach ache, diarrhea.
CNS: drowsiness, dizziness, headache.
Allergic reactions: skin rash, hives, hyperthermia.
Contraindications
- Gastric ulcer and duodenal ulcer in the acute stage;
- Children up to age 3 years;
-hypersensitivity to gvajfenezinu and other components of the drug.
Pregnancy and lactation
The drug should be used with caution during pregnancy and breastfeeding.
Cautions
You should not take the drug Coldrex® Permanent treatment for bronchial cough without a prescription.
The caution should appoint drug patients with gastric bleeding in history, as well as diseases of the bronchi, coupled with the excessive accumulation of phlegm.
The drug Coldrex® Broncho, you can assign simultaneously with other drugs, used in the treatment of bronchopulmonary diseases.
During the period of administration of the drug are advised to take adequate amount of fluid.
It is advisable to combine drug Coldrex® Broncho with posture drainage or vibration massage chest.
During the period of administration the staining of urine in the color pink.
Patients with diabetes should be considered, that the product contains carbohydrates – 3.6 g 5 ml.
Guayfenezin may give false negative results when determining the 5-gidroksiindoluksusnoj and vanililmindal′noj acids in the urine due to the influence of metabolites guayfenezina on color. Reception guayfenezina should stop for 48 hours before urine collection for this analysis.
If the 7 days dose Coldrex® Bronchial cough persists, or along with the temperature rising of cough, skin rash, prolonged headache, sore throat, You should evaluate the feasibility of receiving this drug and hold correction therapy.
Overdose
Symptoms: nausea and vomiting.
Treatment: If you experience vomiting should undertake activities to replenish fluids in the body and monitor the level of electrolytes.
Drug Interactions
While admission Coldrex® Broncho with protivokashlevami drugs, containing codeine, can deteriorate expectoration of sputum liquefied. This combination is not recommended.
Conditions of supply of pharmacies
The drug is resolved to application as an agent Valium holidays.
Conditions and terms
The drug should be stored out of reach of children at or above 30 ° C. Shelf life – 3 year.
