Active material: Ketotifen
When ATH: R06AX17
CCF: Stabilizers fat cell membranes. Allergy medication
When CSF: 13.02.01
Manufacturer: SOPHARMA AD (Bulgaria)
Syrup colorless to pale yellow, clear, Coupling, with a specific smell of strawberries.
| 5 ml | |
| Ketotifen gidrofumarat | 1.38 mg, |
| that corresponds to the content of ketotifen | 1 mg |
Excipients: sorbitol, metilparagidroksiʙenzoat, propilparagidroksibenzoat, citric acid monohydrate, sodium hydrogen phosphate dodecahydrate, ethanol 96%, sodium saccharin, strawberry flavor (жидкая эссенция “Клубника”), Purified water.
100 мл – флаконы темного стекла (1) в комплекте с мерной ложкой или стаканчиком – пачки картонные.
100 мл – флаконы темного полиэтилентерефталата (1) в комплекте с мерной ложкой или стаканчиком – пачки картонные.
Pills white or white with a gray tint, round, flat, with a facet and Valium on the one hand, without smell.
| 1 tab. | |
| Ketotifen gidrofumarat | 1.38 mg, |
| that corresponds to the content of ketotifen | 1 mg |
Excipients: microcrystalline cellulose, calcium hydrogen phosphate, wheat starch, magnesium stearate.
10 PC. – блистеры (3) – пачки картонные.
Antiallergic agent. The mechanism of action is associated with the stabilization of mast cell membranes and decrease the release of histamine from them, leukotrienes and other biologically active substances. Suppresses induced platelet activating factor accumulation of eosinophils in the airways. Prevents asthma attacks, Some other manifestations of allergic reactions immediate type. Blocking histamine H1-receptors.
Once inside almost completely absorbed from the gastrointestinal tract. Simultaneous food intake does not affect the extent of absorption of ketotifen. Metaboliziruetsya of 50% при “первом прохождении” через печень. Cmax plasma levels reached within 2-4 no. Plasma protein binding is 75%.
Displayed dwuhfazno. T1/2 in the initial phase of 3-5 no, в конечной – 21 no. Report the news, 60-70% as metabolites, 1% - Unchanged.
Prevention of allergic diseases, incl. atopic asthma, allergic bronchitis, hay fever, nasal allergy, atopic dermatitis, hives, allergic conjunctivitis.
Is the inside. Взрослым – по 1 mg 2 times / day (in the morning and in the evening) while eating. If necessary, the daily dose can be increased to 4 mg.
The maximum daily dose: для взрослых – 4 mg.
For children 2-3 years - by 1 mg 2 times / day; aged 6 Months before 3 years - by 500 g 2 times / day.
CNS: drowsiness, dizzy, slow mental reactions, usually disappear a few days after the start of treatment.
From the digestive system: possible increased appetite; редко – диспептические явления, dry mouth.
From the hematopoietic system: thrombocytopenia.
From the urinary system: dizurija, cystitis.
Metabolism: weight gain.
Hypersensitivity to ketotifen.
When pregnancy, especially in the I trimester, use is possible only in the case, if the potential benefit to the mother outweighs the potential risk to the fetus.
Ketotifen passes into breast milk, so if you need it, use during lactation should decide the issue of termination of breastfeeding.
The therapeutic effect of ketotifen develops slowly, during 1-2 months.
Conductivity Antiasthma therapy should be continued, at least, during 2 weeks after the start of ketotifen.
With simultaneous use of ketotifen and bronchodilators last dose can sometimes be reduced.
Effects on ability to drive vehicles and management mechanisms
Patients, taking Ketotifenum, We should refrain from potentially hazardous activities, related to the need for increased attention and rapid psychomotor reactions.
Ketotifen may potentiate the effects of sedatives, hypnotics, antihistaminics and ethanol.
When receiving ketotifen concurrently with oral hypoglycemic agents noted a reversible decrease in the number of platelets.
This site uses cookies and services to collect technical data from visitors to ensure performance and improve the quality of service.. By continuing to use our site, you automatically agree to the use of these technologies.
Read More