Isophra: instructions for using the medicine, structure, Contraindications

Active material: Framycetin
When ATH: R01AX08
CCF: Antibacterial drug for local use in ENT practice
ICD-10 codes (testimony): J00, J01, J31, J32, Z29.2, Z29.8
When CSF: 06.05.04
Manufacturer: Laboratoires Bouchara-RECORDATI (France)

Isophra: dosage form, composition and packaging

Spray nazalynыy 1.25%1 ml
framycetin sulfate12.5 mg (8 th. ME)

Excipients: metilparagidroksiʙenzoat, sodium chloride, lemon acid, water distillirovannaya.

15 ml – plastic bottles (1) Included spray – packs cardboard.

Isophra: pharmachologic effect

Aminoglycoside antibiotic for topical use in otorhinolaryngology. Effective bactericidal. It is active against Gram-positive and Gram-negative bacteria, causing the development of infectious processes in the upper respiratory tract.

Isophra: pharmacokinetics

Research pharmacokinetics Izofra not conducted in connection with low systemic absorption.

Isophra: testimony

In the combined therapy in infectious and inflammatory diseases of the upper respiratory tract, including:

  • rhinitis;
  • rinofaringitы;
  • sinusitis (in the absence of damage to walls);

Prevention and treatment of inflammatory processes after surgery.

Isophra: dosing regimen

Adults appoint 1 injection into each nostril 4-6 time / day.

Babies appoint 1 injection into each nostril 3 times / day.

The average duration of therapy – 7 days.

By drinking a bottle should be kept in the upright position.

Isophra: side effects

Allergic reactions: in a few cases – cutaneous manifestations.

Isophra: Contraindications

  • hypersensitivity to framycetin and other antibiotics from the aminoglycoside group.

Isophra: Pregnancy and lactation

Adequate and well-controlled clinical studies safety of the drug Izofra during pregnancy and lactation (breast-feeding) not performed.

Isophra: Special instructions

If during the 7 days of treatment with a therapeutic effect is weak or absent, the drug should be abolished.

Isophra: overdose

Due to the low degree of absorption into the systemic circulation overdose is unlikely.

Isophra: drug interaction

No clinically significant drug interactions Izofra with other drugs have been identified.

Isophra: terms of dispensing from pharmacies

The drug is released under the prescription.

Isophra: terms and conditions of storage

The drug should be stored at temperatures above 25 ° C. Shelf life – 3 year.

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