GEKSORAL

Active material: Geksetidin
When ATH: A01AB12
CCF: With antibacterial drug, antifungal and hemostatic action for local application in an ENT-practice and stomatology
ICD-10 codes (testimony): A69.1, B37.0, J02, J03, J31, J35.0, K05, K12, R19.6, Z29.8
When CSF: 24.01.06
Manufacturer: JOHNSON & JOHNSON LTD (Russia)

Pharmaceutical form, composition and packaging

◊ Spray for topical use 0.2% as a clear syrupy liquid, almost colorless, with the smell of menthol.

Excipients: citric acid monohydrate, sodium saccharin, Sodium hydroxide, glycerol, lauromacrogol (Winners 23), mint flavor (33C071) (menthol, peppermint oil, anethole, eucalyptol, ethyl formate, propylene glycol), Purified water.

40 ml – aluminum aerosol cans (1) complete with nozzle spray – packs cardboard.

◊ Solution for topical application 0.1% clear, of red color, with the smell of mint.

Excipients: ethanol 96% (4.33 g / 100 ml), polysorbate 60, peppermint oil, anise oil, citric acid monohydrate, sodium saccharin, levomenthol, Methyl salicylate, clove oil, eucalyptus oil, azoruʙin 85% (E122), Purified water.

200 ml – glass bottles (1) – packs cardboard.

Pharmacological action

Antiseptic preparation for local application in an ENT-practice and stomatology. The antimicrobial effect of the drug due to the suppression of oxidation reactions of metabolism of bacteria (antagonist thiamine).

The drug has a broad spectrum of antibacterial action (incl. against gram-positive bacteria) and antifungal activity (incl. against fungi of the genus Candida).

Geksoral^® It may also have an effect in the treatment of infections, caused by Pseudomonas aeruginosa or Proteus spp.

The concentration 100 mg / mL drug suppresses most bacterial strains. Development of resistance was not observed.

Geksetidin has little effect on the anesthetic mucosa.

Pharmacokinetics

Geksetidin very well adheres to the mucosa and practically not absorbed.

After a single application of the active substance is detected in the mucosa of the gums during 65 no. The plaque on the teeth active concentrations persist for 10-14 no after application.

Testimony

- Inflammatory and infectious diseases of the oral cavity and pharynx;

- In the complex treatment of severe febrile or septic diseases oral cavity and pharynx, requiring antibiotics and sulfonamides, tonsillitis;

- Sore throat (incl. angina with lesions of the lateral rollers, Angina Plaut-Vincent);

- Pharyngitis;

- Gingivitis and krovotochivostь right;

- Periodontopatii;

- Stomatitis, glossitis, aphthous ulcers to prevent superinfection;

- Infection of the alveoli after tooth extraction;

- Fungal infection of the mouth and pharynx, especially thrush;

- Before and after surgery in the oral cavity and pharynx;

- Additional oral hygiene with the common diseases;

- The elimination of halitosis, especially in the case of destruction of tumors of the mouth and throat;

- An adjunct in the treatment of colds.

Dosage regimen

The drug is applied topically.

When applying a topical aerosol adults and children over 3 years single dose administered over 1-2 sec.

When applying a topical solution should rinse the mouth and throat 15 ml undiluted solution for 30 sec.

The drug is prescribed 2 times / day (preferably in the morning and evening), postprandial. Safe at more frequent use.

The duration of treatment is determined by a physician.

Terms of use of the drug

When using an aerosol topical drug is sprayed into the mouth or pharyngeal. With the help of aerosol can be easily and quickly process the affected areas. You must perform the following steps:

1. Set spray tube in a corresponding opening top of the vial, easily pushing it, the tip of the tube to direct myself.

2. Hold the spray tube, send it to the affected area of ​​the mouth or throat.

3. During insertion bottle must be held constantly in a vertical position.

4. Enter the desired amount of drug, pushing the head during 1-2 from, not to breathe the introduction of aerosol.

Solution for local application can only be used for rinsing the mouth and throat. The solution can not swallow. To rinse, always use undiluted solution. In the treatment of oral ailments solution can also be applied by a swab.

Side effect

IN some cases may develop hypersensitivity reactions to the drug; long-term use may be in breach of taste.

Contraindications

- Children up to age 3 years;

- Hypersensitivity to any component of the drug.

Pregnancy and lactation

Data about any damaging effects of the drug Geksoral^® pregnancy and lactation No. Nonetheless, before the appointment Geksoral^® pregnant or nursing women physician should carefully weigh the benefits and risks of treatment, given the lack of sufficient data on the penetration of the drug through the placenta and breast milk.

Cautions

The drug Geksoral^® in the form of a solution for topical use can be used for rinsing the oral cavity and pharynx only, If the patient can spit after rinsing solution.

The drug Geksoral^® topical solution contains ethanol 96% (4.33 g / 100 ml).

Use in Pediatrics

Children can use the drug with such age, when there is no danger of uncontrolled swallowing it when applying solution for local use or when they do not resist foreign objects (applicator) in the mouth when using spray for topical use and can hold their breath during injection preparation.

Overdose

Geksetidin in said non-toxic dose. Ingestion of large amounts of the drug leads to vomiting, therefore, a significant absorption is not expected. No cases of alcohol poisoning in overdose has not been described. Acute alcohol poisoning is very unlikely, but it is theoretically possible if swallowed a large dose a small child.

Treatment: symptomatic therapy (as in alcohol intoxication). Gastric lavage is necessary for 2 hours after ingestion of an overdose.

In all cases of overdose the patient should be informed, it should immediately consult a doctor.

Drug Interactions

Drug Interactions drug Geksoral^® not disclosed.

Conditions of supply of pharmacies

The drug is resolved to application as an agent Valium holidays.

Conditions and terms

The drug should be stored out of reach of children at or above 25 ° C. Shelf life – 2 year.