Active material: Fusidic acid
When ATH: D06AX01
CCF: Antibiotics for topical use
ICD-10 codes (testimony): L08.0, L30.3
When CSF: 06.15.01
Manufacturer: LEO PHARMACEUTICAL PRODUCTS (Denmark)
Cream for external application 2% homogeneous, white.
| 1 g | |
| fusidic acid anhydrous | 20 mg |
Excipients: ʙutilgidroksianizol, cetyl alcohol, glycerol 85%, Liquid paraffin, potassium sorbate, polysorbate 60, white soft paraffin, Purified water.
15 г – тубы алюминиевые (1) – пачки картонные.
Ointment for external application 2% Homogeneous, translucent, white to yellowish-white.
| 1 g | |
| sodium fusidate | 20 mg |
Excipients: Nipple, cetyl alcohol, Liquid paraffin, white soft paraffin.
15 г – тубы алюминиевые (1) – пачки картонные.
It refers to a group fuzidinu, antimicrobial compounds, mechanism of action which is associated with the violation of protein synthesis in the bacterial cell. By blocking the elongation factor G, they prevent it from binding to ribosomes and guanosine, that interrupts the release of energy, necessary for protein synthesis, and leads to the death of the bacterial cell.
To sodium fusidate sensitive Gram-positive bacteria (Staphylococcus aureus, Streptococcus pyogenes, Corynebacterium minute), Gram negative bacteria (Pseudomonas spp.).
No reports of cross-resistance to sodium fusidate.
Permeability fusidic acid through the intact skin and of low 0.54% of the applied amount of the drug.
- Bacterial skin infections in adults, Adolescents, children's and baby.
The cream and ointment applied to the affected skin 3 times / day for 10 days.
Dermatological reactions (listed in descending order of frequency of occurrence): itch, irritation, burning sensation and tingling, xerosis, rash (эritematoznaya, macular-papular, pustular), contact dermatitis, eczema, эritema, periorbital edema.
Allergic reactions: hives, angioedema.
The incidence of side effects related to the very rare and is 2:1 000 000 treatments.
- Hypersensitivity to the drug.
With care prescribe a drug during pregnancy and lactation (breast-feeding).
B experimental studies found, fusidic acid that does not have embryotoxic and teratogenic effects.
When using Fucidinum® ointment on the face should be careful, tk. After eye fusidate sodium causes irritation of the conjunctiva.
Data on drug overdose Fucidinum® not provided.
Drug Interactions drug Fucidinum® not disclosed.
The drug is released under the prescription.
List B. The drug should be stored out of reach of children at or above 25 ° C. Shelf life - 3 year.
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