Active material: Karʙoцistein
When ATH: R05CB03
CCF: Mucolytic drugs
ICD-10 codes (testimony): H66, J00, J01, J04, J15, J20, J31, J32, J37, J42, J45, J47, Z51.4
When CSF: 12.02.01
Manufacturer: Laboratoire INNOTECH INTERNATIONAL (France)
◊ Syrup 2% for children as a clear orange liquid with the odor of banana.
| 5 ml | |
| karʙoцistein | 100 mg |
Excipients: sucrose, Banana flavor, metilparagidroksiʙenzoat, glycerol (glycerol), Sodium hydroxide, yellow-orange dye S, Purified water.
125 мл – флаконы стеклянные (1) – пачки картонные.
◊ Syrup 5% as a clear liquid of light green color with a brown tint, with the smell of caramel.
| 15 ml | |
| karʙoцistein | 750 mg |
Excipients: sucrose, caramel flavor, metilparagidroksiʙenzoat, glycerol (glycerol), Sodium hydroxide, yellow-orange dye S, Purified water, patent blue dye.
125 мл – флаконы стеклянные (1) – пачки картонные.
Mucolytic drugs. Муколитическое и отхаркивающее действие обусловлено активацией сиаловой трансферазы – фермента бокаловидных клеток слизистой оболочки бронхов. It normalizes the proportion of acid and neutral sialomutsinov bronchial secretions, restores strength and elasticity of the mucus. It promotes the regeneration of the mucous membrane, normalizes its structure, activates the activity of ciliated epithelium. Restores the secretion of immunologically active IgA (specific protection) and the number of sulfhydryl groups of components of mucus (nespetsificheskaya protection), improves mucociliary clearance.
Absorption
After oral administration, Cmax in serum and respiratory mucosa is achieved after 2-3 hours after ingestion and is stored in the mucosa during 8 no.
Deduction
Write mainly with urine, частично – в неизмененном виде, частично – в виде метаболитов.
- Acute and chronic bronchopulmonary diseases, accompanied by the formation of a viscous, sputum (tracheitis, bronchitis, traheobronhit, bronchial asthma, bronchiectasis);
- Acute and chronic inflammatory diseases of the middle ear, the nose and paranasal sinuses, accompanied by the formation of a viscous, trudnootdelyaemoy mucus (rhinitis, otitis media, sinusitis);
- Preparation for bronchoscopy and / or bronhografii.
Syrup 2% for children
1 tea spoon (5 ml) It contains 100 mg carbocisteine.
Children aged 1 Months before 2 years appointed 1 teaspoon (5 ml) 1-2 times / day, without exceeding the dose 20-30 mg / kg body weight / day; children aged 2 to 5 years appointed 1 teaspoon (5 ml) 2 times / day; older children 5 years appointed 1 teaspoon (5 ml) 3 times / day. Treatment should not last more than 8-10 days without consulting a doctor.
Syrup 5%
1 tablespoon (15 ml) It contains 750 mg carbocisteine.
Children over 15 years and adults appoint 1 tablespoon (15 ml) 3 times / day, it is desirable to empty stomach or after 2 h postprandial. Treatment should not last more than 8-10 days without consulting a doctor.
From the digestive system: иногда – тошнота, vomiting, diarrhea, epigastric pain, flatulence, gastrointestinal bleeding.
CNS: dizziness, weakness, malaise.
Allergic reactions: в единичных случаях – зуд, hives, rash, angioedema.
- Gastric ulcer and duodenal ulcer in the acute phase;
- Chronic glomerulonephritis (exacerbation), cystitis;
- Children up to age 1 Months (syrup 2% for children) and to 15 years (syrup 5%);
- I trimester of pregnancy (syrup 5%);
- Hypersensitivity to Karbotsistein or other ingredients.
FROM caution should be prescribed for chronic glomerulonephritis (history), gastric ulcer and duodenal ulcer (history), II and III trimester of pregnancy and breast-feeding.
Use of the drug Flyuditek® I trimester of pregnancy is contraindicated.
Precautions should be prescribed Flyuditek® II and III trimester of pregnancy and breast-feeding.
It should be taken into account, that the presence of the banana flavor syrup 2% Children may be the cause of allergic reactions in young infants.
Patients with diabetes or are on a low-carb diet should be taken into account, what 1 teaspoon syrup 2% Children contains 3.5 g sucrose, and 1 tablespoon syrup 5% It contains 5.25 g sucrose. The presence of sucrose may be the cause of flatulence and indigestion in infants.
At low salt or salt-free diet should take into account the sodium content in the product.
Flyuditek® in the form of a syrup 5% It is only intended for adults and older children 15 years.
Symptoms: gastralgia, nausea, diarrhea.
Treatment: symptomatic therapy.
In an application Flyuditek® improves glucocorticosteroid (mutually) and antibiotic treatment of inflammatory diseases of the upper and lower respiratory tract.
In an application Flyuditek® enhances bronchodilator effect of theophylline.
Activity carbocisteine weaken antitussive agents and atropine.
The drug is resolved to application as an agent Valium holidays.
The drug should be stored out of reach of children at or above 25 ° C. Shelf life - 2 year.
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