FLOGÉNZIM

Active material: Bromelain, Rutozid, Trypsin
When ATH: M09AB52
CCF: The drug with anti-inflammatory action
ICD-10 codes (testimony): B18.1, B18.2, i20, I73.0, I73.1, I73.9, I80, I82, I87.0, K73, M02, M05, M45, M79, N10, N11, N30, N34, N41, N70, T14.3, T30, Z29.8
When CSF: 05.03.01
Manufacturer: MUCOS PHARMA GmbH&Co (Germany)

Pharmaceutical form, composition and packaging

◊ Pills, enteric coated greenish yellow, round, lenticular, with smooth surface, with a characteristic odor; slight deviations from uniformity in colouring the shell (marbling picture, pinpoint inclusions).

Excipients: lactose hydrate, corn starch, magnesium stearate, stearic acid, Purified water, Colloidal anhydrous silica, talc.

The composition of the shell tablets: macrogol 6000, methacrylic acid – methyl methacrylate copolymer (1:1), talc, triэtiltsitrat, vanillin.

20 PC. – blisters (2) – packs cardboard.
20 PC. – blisters (5) – packs cardboard.
20 PC. – blisters (10) – packs cardboard.
800 PC. – bottles of high density polyethylene.

Pharmacological action

Flogjenzim is a combination of enzymes (Bromelain and trypsin) and routine. Bromelain and trypsin contribute to the rapid breakdown of cell fragments and metabolic products of inflammation, rutin restores the permeability of vascular walls, that leads to a decrease of edemas and hematomas.

Flogjenzim anti-inflammatory, fibrinolytic, antiagregantnoe, immunomodulatory and antitumor activity, comprehensively influencing physiological and pathophysiological processes.

Improves functional status of blood cells and the vascular wall; reduces the viscosity of blood and the risk of blood clots in the vessels, contributes to lizisu already formed blood clots. Improves Microcirculation in hotbeds of chronic inflammation, improves delivery of oxygen and nutrients, thus stimulating reparative processes in chronic diseases and in the postoperative period. As a result, reduces swelling, hematoma and dissipates quickly reduced pain syndrome.

Flogjenzim improves blood circulation of the bronchi and lungs in chronic diseases of the upper respiratory tract, incl. caused by smoking; anise, improves function mertzatelnogo cancer and restores the drainage function of the bronchi.

The drug increases the effectiveness of antibiotics.

Pharmacokinetics

After taking the inside are poorly studied, members of the drug absorbed from the small intestine enzymes by resorption intact molecules and, binding to transport proteins of blood, Enter the bloodstream. Then enzymes, migrating on the vascular bed, It accumulates in the area of ​​pathological process, regardless of the localization in the body.

Testimony

In the combined therapy:

— treatment of postoperative complications in surgery, Dentistry and in plastic surgery (suppuration, thrombosis, Spikes); with the aim of preventing adhesive disease, lymph edema, Microcirculatory disorders; burns;

-tendon injuries, ligaments, sports injuries;

- Treatment of acute deep vein thrombosis, thrombophlebitis of superficial veins, postflebiticheskogo syndrome, chronic arteriopatij (incl. obliterating atherosclerosis of the arteries of the lower limbs);

-treatment of acute and chronic inflammations of the urinary tract (uretrit, cystitis, cystopyelitis, prostatitis);

-treatment of acute and chronic pelvic inflammatory disease (adnexitis, salpingo-oophoritis), Vascular complications of menopause, to reduce the frequency and severity of side effects of hormone replacement therapy in gynecology;

- CHD, prevention of angina attacks;

- Chronic hepatitis;

- Rheumatoid arthritis, ankylosing spondylitis, reactive arthritis, rheumatic soft tissue.

Dosage regimen

Adults with the aim of treatment the drug is prescribed for 3 tab. 3 times / day for 2 weeks.

With the aim of preventing It is recommended that you use 2 tab. 3 times / day for 2 weeks.

Changing the dosage or treatment the doctor determines individually.

The tablets should be taken at least 30 minutes before eating, without chewing, drinking water (200 ml).

Side effect

Flogjenzim is well tolerated by patients. In some cases, There are frequent stool, change the texture and smell of feces, which quickly cease upon a temporary decrease in dosage. Rarely allergical reactions (skin rash, itch), that disappear after discontinuation of treatment with. In applying the drug experienced nausea, flatulence, stomach ache, headache, dizziness, rash, generalized weakness. You may experience temporary sensations bowel overflow. This can be prevented, dividing the daily dose for a larger number of single doses.

Contraindications

is congenital or acquired human blood clotting (incl. hemophilia);

- Children's age (no experience of);

- Individual intolerance to the drug.

FROM caution applied to dialysis.

Pregnancy and lactation

The caution should be appointed Flogjenzim in pregnancy and lactation.

Cautions

When infectious-inflammatory diseases of Flogjenzim does not replace antibiotic treatment.

An exacerbation of symptoms in the face of the reception are poorly studied, but recommended a temporary dose reduction. In such cases, the patient must consult a doctor.

The drug is not a doping.

Effects on ability to drive vehicles and management mechanisms

The drug has no negative impact on the ability to drive a car and perform work, requiring a high rate of psychomotor reactions.

Overdose

The cases of drug overdose Flogjenzim were reported.

Drug Interactions

Together with the admission of antibiotics Flogjenzim increases the effectiveness of antibiotics.

Incompatibilities are poorly studied, with other drugs are not indicated.

Conditions of supply of pharmacies

The drug is resolved to application as an agent Valium holidays.

Conditions and terms

List B. The drug should be stored out of reach of children, at a temperature from 15 ° to 25 ° C.. Shelf life – 3 year.