FLEKSITAL

Active material: Pentoxifylline
When ATH: C04AD03
CCF: Preparation, improving microcirculation. Angioprotektor
When CSF: 01.14.01
Manufacturer: Sun Pharmaceutical Industries Ltd. (India)

PHARMACEUTICAL FORM, COMPOSITION AND PACKAGING

Pills, enteric-coated film-coated of blue color, round.

Excipients: lactose, corn starch, microcrystalline cellulose, sodium lauryl, povidone K-30, Talcum cleared, magnesium stearate, Colloidal anhydrous silica, acrylic acid copolymer type in, acrylic acid copolymer type with, dibutyl phthalate, Titanium dioxide, macrogol 6000, colorant brilliant blue.

10 PC. – strips of aluminum foil (6) – packs cardboard.

Pharmacological action

The drug improves microcirculation and blood rheology. The mechanism of action is associated with inhibition of the enzyme Phosphodiesterase, which leads to the accumulation of c-AMP in cells.

Fleksital increases the flexibility of red blood cells, reduces adhesion, reduces agregatia platelets and blood viscosity. It has a vasodilating effect

Testimony

• peripheral circulatory disorders (incl. complicated trophic violations tissues, associated with the microvascular arteries or veins, varicose veins, otmorozheniem);
• cerebrovascular accidents (incl. Ischemic cerebral stroke, violation of blood supply to the brain due to atherosclerosis, encephalopathy);
• diabetic angiopathy;
• violation of blood supply to the retina (incl. due to central retinal artery thrombosis).

Dosage regimen

Inside designate, depending on the severity of the disease, dose 300-1600 mg / day 3 admission.

Injection administered in/and, w / w or w / o.

B/a drip to impose on 100-300 mg (in 20-100 ml 0.9% sodium chloride solution) during 10-30 m 1 time / day.

In/in or/and Jet injected 100 mg medication for 5-10 m (in the supine position) 1-2 times / day.

In/in struino injected 50 mg (in 10 ml 0.9% sodium chloride solution) during 10 m, then / drip – 100 mg (in 250-500 ml 0.9% sodium chloride solution or 5% glucose solution) during 90-180 m.

If necessary dose can be increased to daily 50-100 mg to achieve a daily dose of 300 mg. In severe cases it is permissible to introduction 400 mg/day for two receptions.

/ M (deep) appoint 100-200 mg 2-3 times / day.

Simultaneously with the introduction of intravenous medication inside can be assigned to a daily dose of 800-1200 mg 2-3 admission.

Side effect

On the part of the digestive tract: dyspepsia, vomiting.

Cardio-vascular system: palpitations, tachycardia, flushing of the skin; You may decline ad (in/in or/and introduction).

From the nervous system: dizziness, headache, nervousness, drowsiness or insomnia.

Allergic reactions: skin rash.

Other: rarely – increased brittleness of nails, weight change, bleeding

Contraindications

Absolute:

• acute myocardial infarction;
• massive bleeding;
• retinal hemorrhage.

Relative:

• expressed arteriosclerosis cerebrovascular and heart;
• expressed by cardiac arrhythmia (for / in the);
• pregnancy;
• lactation.

Pregnancy and lactation

Use of the drug during pregnancy is possible only in case, when the intended benefits to the mother outweighs the potential risk to the fetus.

If necessary, the appointment during lactation should decide the issue of termination of breastfeeding.

Cautions

The drug is not recommended to appoint simple diabetic retinopathy.

In appointing the drug should monitor the level of HELL. With the appointment of Fleksitala at the same time as antikoagulyantami, you must carefully monitor indicators of blood coagulation.

Overdose

Currently, the cases of drug overdose Fleksital were reported.

Drug Interactions

Drug potenziruet antigipertenziveh funds, insulin, oral gipoglikemizirujushhih drugs. Dose Fleksitala in these cases should reduce.

Conditions and terms

The drug should be stored in a dry, dark place at a temperature no higher than 25 ° C.

Storage life – 4 year.