FERVEX FOR CHILDREN

Active material: Vitamin C, Paracetamol, Pheniramine
When ATH: N02BE51
CCF: The drug for the symptomatic treatment of acute respiratory diseases
ICD-10 codes (testimony): J00, J06.9, J10, J30.1
When CSF: 03.02.01.03
Manufacturer: BRISTOL-MYERS SQUIBB (France)

Pharmaceutical form, composition and packaging

◊ Powder for oral solution light yellow color with yellow patches, with a characteristic odor.

Excipients: sucrose, riboflavin sodium phosphate, trimagnesium dicitratobismuthate Anhydrous, Aspartame, banana-caramel flavor.

3 g – packets of the composite material (6) – cardboard boxes.
3 g – packets of the composite material (8) – cardboard boxes.

Pharmacological action

Combined preparation, kotorыy soderzhit paracetamol and pheniramine maleate. Analgesic , antipyretic and antihistamine action. Vitamin C, part of the Fervex children, takes part in the regulation of redox processes, It reduces the permeability of blood vessels and increases the body's resistance.

Pharmacokinetics

Data on the pharmacokinetics Fervex for children are not provided.

Testimony

To children aged 6 to 15 years for short-term treatment of conditions, accompanied by:

- Fever, moderate pain, rhinitis for colds;

- Rhinitis and nasopharyngitis infectious and inflammatory and allergic nature.

Dosage regimen

The drug is prescribed inside. The dose depends on the age of the child:

Children 6 to 10 years – by 1 paketiku 2 times / day;

Children 10 to 12 years – by 1 paketiku 3 times / day;

Children 12 to 15 years – by 1 paketiku 4 times / day.

The interval between doses of the drug is not less than 4 no. Duration of treatment – no more 5 days.

Before taking the contents of the sachet should be dissolved in a glass (200 ml) warm water.

Side effect

From the digestive system: possible dry mouth, nausea, vomiting, stomach ache, constipation; long-term use at doses, than recommended, possible hepatotoxic effects.

From the urinary system: may be a delay of urination; long-term use at doses, than recommended, possible nephrotoxicity.

From the hematopoietic system: rarely – anemia, leukopenia, agranulocytosis, thrombocytopenia; long-term use at doses, than recommended – gemoliticheskaya anemia, aplasticheskaya anemia, metgemoglobinemiâ, pancytopenia.

Allergic reactions: possible skin rash, itch, hives, angioedema.

Other: drowsiness.

The drug was well tolerated at recommended doses.

Contraindications

- Severe liver;

- Severe renal dysfunction;

- Blood disorders;

- Deficit ferment glucose-6-fosfatdegidrogenazы;

- Children up to age 6 years;

- Hypersensitivity to the drug.

FROM caution use in patients with abnormal liver function or kidney, when Gilbert's syndrome, for patients with diabetes.

Cautions

Fervex children should not be used concomitantly with other drugs, soderzhashtimi paracetamol.

In applying the drug more than a week is necessary to control the functional state of the liver and peripheral blood picture.

In the case of dosing children, diabetes mellitus, or located on a diet with low sugar content, should be considered, that each packet contains 2.4 g sugar.

Paracetamol distorts the results of laboratory studies of glucose and uric acid in the blood plasma.

In the absence of the therapeutic effect (hyperthermia lasting over 3 days and a painful syndrome 5 days) requires medical consultation.

Overdose

Symptoms: anorexia, nausea, vomiting, stomachache, Sweating, pale skin, drowsiness. Through 1-2 day show signs of liver damage. In severe cases develop liver failure, gepatonekroz, encephalopathy and coma.

Treatment: recommended gastric lavage, reception enterosorbents (Activated carbon, Polyphepanum), / in the introduction of the antidote N-acetylcysteine, reception methionine. It is necessary to monitor the patient's condition.

Drug Interactions

Fervex children, by a member of the pheniramine maleate, enhances the effect of sedatives. When used together with antipsychotics (phenothiazines) increased risk of adverse drug events (urinary retention, dry mouth, constipation).

In applying Fervex children, soderzhashtego paracetamol, concurrently with barbiturates, tricyclic antidepressants, anticonvulsants (phenytoin), ziksorinom, phenylbutazone, rifampicin and ethanol significantly increased risk of hepatotoxicity.

Reception in conjunction with salicylates increase the risk of nephrotoxicity.

In an application with chloramphenicol (chloramphenicol) the toxicity of the latter increases.

Paracetamol, contained in the product, enhances the effect of indirect anticoagulants; reduces the effectiveness of drugs urikozuricheskih.

Conditions of supply of pharmacies

The drug is resolved to application as an agent Valium holidays.

Conditions and terms

The drug should be stored out of reach of children, dry place at temperatures no higher than 25 ° C. Shelf life – 3 year.