Fenistil PENCIVIR

Active material: Penciclovir
When ATH: D06BB06
CCF: Antivirals for outdoor use
ICD-10 codes (testimony): B00
When CSF: 09.02.01
Manufacturer: NOVARTIS PHARMA PRODUCTIONS GmbH (Germany)

Pharmaceutical form, composition and packaging

◊ Cream for external application 1% uniform, white.

Excipients: tsetomakrohol 1000, cetostearyl alcohol, white soft paraffin, Oil vaseline (Liquid paraffin), propylene glycol, Purified water.

2 g – aluminum tuba (1) – packs cardboard.
2 g – aluminum tuba (1) – Plastic canisters complete with mirror and applicator (20 PC.).
5 g – aluminum tuba (1) – packs cardboard.
5 g – aluminum tuba (1) – Plastic canisters complete with mirror and applicator (20 PC.).

Pharmacological action

Antivirals for outdoor use. Penciclovir – viricide, active against Herpes simplex viruses 1 and 2 type, вируса Varicella zoster. The virus may be present in an inactive form in the body for a long time. Upon activation (eg, due to fatigue, colds, Flu) the virus begins to multiply, that leads to the development of fever blisters, particularly often observed on the lips or in areas around them. Penciclovir prevents viruses and stops its reproduction. Use of the drug leads to more rapid recovery, decrease in the intensity of pain, reduced period of risk of viral transmission.

Pharmacokinetics

For external use drug undergoes virtually no systemic absorption. Modern analytical methods can not identify penciclovir in the blood or urine of healthy volunteers after applying the cream Fenistil^® Pentsivir doses, many times the therapeutic.

Penetrating into the virus-infected cells, penciclovir quickly turns into penciclovir triphosphate, exhibit pharmacological activity and are stored in the affected cells for 12 no.

Testimony

- Recurrent herpes simplex on the lips with a localization (herpes labialis).

Dosage regimen

The drug is used topically. Adults and for children 12 and older: a small amount of cream is extruded onto the fingertip and applied to the affected area every 2 no (about 8 time / day). The course of treatment is carried out for 4 days.

The cream can also be applied with a cotton swab or a disposable applicator (For packages, containing applicators).

Side effect

Local reactions: possible burning, tingling or numbness immediately after application of the drug.

Contraindications

- Children up to age 12 years;

- Hypersensitivity to penciclovir, famciclovir or other ingredients.

Pregnancy and lactation

Application during pregnancy is possible on strict in cases, the expected benefit to the mother outweighs the potential risk to the fetus.

If necessary, use during lactation is required to consult a doctor.

Cautions

You must wash your hands thoroughly before and after applying the cream.

Treatment should begin as soon as possible, at the first sign of infection. Nonetheless, even at the stage of development of the herpes vesicles applying cream Fenistil^® Pentsivir reduces the time a cure (It heals the affected areas, It reduces pain and shortens the duration of flaking crust, resulting from exposure to the virus).

In immunocompromised patients, or if the manifestations of the disease are uncertain, the need for the drug the doctor decides individually.

The drug should be used only on the affected areas herpes on the lips and skin around the mouth. Do not apply the cream on the oral mucosa, the nose or the eyes and genitals.

It is necessary to conduct a full course of therapy with a cream Fenistil^® Pentsivir for 4 days, In order to achieve the greatest effect of the therapy, Even if signs of infection disappear after one or two days of treatment.

At deterioration or no improvement after 4 days of treatment, the patient should consult the doctor

Effects on ability to drive vehicles and management mechanisms

Not observed any effect of the drug on the ability to drive vehicles and operating machinery.

Overdose

No cases of overdose were reported.

Drug Interactions

Any drug interactions Fenistil cream^® Pentsivir unknown.

Conditions of supply of pharmacies

The drug is resolved to application as an agent Valium holidays.

Conditions and terms

The drug should be stored out of reach of children at or above 30 ° C. Do not freeze. Shelf life – 3 year.