Penciclovir

When ATH:
D06BB06

Characteristic.

White or pale yellow solid,. Solubility in 20 °C: in methanol is 0,2 mg / ml, in propilenglikole — 1,3 mg / ml, in the water- 1,7 mg / ml. The aqueous buffer (pH 2) solubility is 10,0 mg / ml. Not hygroscopic. Coefficient of n-octanol / water at pH 7,5 is equal to 0,024.

Pharmacological action.
Antiviral, antiherpetic.

Application.

Recurrent cold sores on the lips with a localization (Herpes labialis).

Contraindications.

Hypersensitivity, Age to 16 years.

Pregnancy and breast-feeding.

Use during pregnancy is possible on strict in cases, the expected benefit to the mother outweighs the potential risk to the fetus.

Category actions result in FDA - B. (The study of reproduction in animals revealed no risk of adverse effects on the fetus, and adequate and well-controlled studies in pregnant women have not done.)

If necessary, use during lactation is necessary to consult a doctor.

Side effects.

Burning, paresthesia, numbness at the site of application, allergic reactions.

Dosing and Administration.

Outwardly. Adults and children over 16 years — put on a rash every 2 h during the day 4 days.

Precautions.

Should not be applied to mucous membranes or to the skin around the eyes. Avoid contact with eyes.