ESLIDIN®

Active material: Methionine, polyunsaturated phospholipids from soybean lecithin
When ATH: A05C
CCF: Gepatoprotektor
ICD-10 codes (testimony): E10, E11, I67.2, K70, K71, K73, K74, L40
When CSF: 11.16.01
Manufacturer: NIZHFARM of (Russia)

Pharmaceutical form, composition and packaging

Capsules hard gelatin, №0, the housing of a light brown color and a lid brown; contents of capsules – yellow-brown or brown homogeneous mass of pasty to a solid consistency with a characteristic odor.

Excipients: soybean oil.

Ingredients of the capsule shell: Titanium dioxide, iron oxide black, iron oxide red, iron oxide yellow, Purified water, gelatin.

10 PC. – packings Valium planimetric (3) – packs cardboard.
10 PC. – packings Valium planimetric (5) – packs cardboard.
10 PC. – packings Valium planimetric (6) – packs cardboard.
10 PC. – packings Valium planimetric (10) – packs cardboard.
30 PC. – plastic jars (1) – packs cardboard.
50 PC. – plastic jars (1) – packs cardboard.
60 PC. – plastic jars (1) – packs cardboard.
100 PC. – plastic jars (1) – packs cardboard.
30 PC. – jars, glass (1) – packs cardboard.
50 PC. – jars, glass (1) – packs cardboard.
60 PC. – jars, glass (1) – packs cardboard.

Pharmacological action

Combined preparation, It has hepatoprotective effect, normalizes all types of metabolism (adipose, proteinaceous, carbohydrate).

Methionine, one of the active components of the preparation, – it is an essential amino acid, which is a source of methyl groups moving. Methionine is essential for choline synthesis. The increase of choline increases the synthesis of endogenous (internal) phospholipids and reduce deposition in the liver neutral fat. Methionine is also required for neutralization of xenobiotics. Atherosclerosis reduces the concentration of cholesterol and phospholipids concentration increases blood.

Essential phospholipids – it is essential factors for the development and functioning of liver cells. The main faction of essential phospholipids in the formulation presented phosphatidylcholine (73%), which is the main component of biological membranes. Once in the body, phosphatidylcholine restores the integrity of the membranes of affected cells of the liver and activates a membrane enzymes fosfolipidzavisimye, thereby normalizing the permeability and increasing the detoxification and excretory capacity of the liver cells.

Methionine is essential phospholipids and reinforce each other's action, a source of endogenous and exogenous phospholipids, respectively, improve the functional state of the liver cells and exert hepatoprotective effect.

Methionine is also involved in the metabolism of sulfur-containing amino acids, in the synthesis of epinephrine, creatinine and other biologically active compounds, converts the action of hormones, vitamins (IN₁₂, ascorbic, folic acid), enzymes, proteins, participate in reactions peremetilirovaniya, deamination, decarboxylation.

Eslidin^® restores the function of the liver, enhances its ability to detoxication, and normalizes fat, carbon and protein metabolism.

Pharmacokinetics

The data on the pharmacokinetics Eslidin^® not provided.

Testimony

The drug is used in gastroenterology, Dermatology, Neurology, Cardiology.

- Fatty liver of different etiology;

- Acute and chronic hepatitis (except virus);

- Cirrhosis of the liver;

- Hepatotoxicity (alcoholic, narcotic, drug);

- Violation of the hepatocytes (as a complication of other diseases);

- Before- and aftercare in operations in hepatobiliary area;

- Psoriasis (in the complex therapy);

- Cerebral atherosclerosis (in the complex therapy);

- Coronary atherosclerosis (in the complex therapy);

- Diabetes (in the complex therapy);

- Depletion, dystrophy.

Dosage regimen

The drug is taken orally, while eating. The capsules should be swallowed whole, drinking plenty of water.

At liver diseases, atherosclerosis of the coronary arteries and blood vessels of the brain, diabetes, degeneration and exhaustion appoint 2 capsules 3 times / day. The recommended course of treatment – 3 Months, minimum rate – 1 Months.

At psoriaze – by 2 capsules 3 times / day. The recommended course of treatment – 2 of the week.

Children over 7 years at liver diseases, diabetes, fatty liver – by 2 capsules 3 times / day for 1-3 Months.

At psoriaze older children 7 years – by 2 capsules 3 times / m for 2 weeks.

Children from 3 to 7 years appoint 1 capsule 3 twice daily for 1-3 Months.

Side effect

There are allergic reactions.

Contraindications

- Severe hepatic impairment, hepatic encephalopathy;

- Viral hepatitis;

- Children up to age 3 years;

- Hypersensitivity to the drug.

FROM caution the drug should be used during pregnancy, in children between the ages of 3 to 7 years, in renal failure (due to the risk of increase hyperasotemia).

Pregnancy and lactation

The study confirms the safety Eslidina^® for the safety of the fetus and child during breastfeeding has not been.

Use of the drug during pregnancy and lactation is possible only on prescription in cases, when the intended benefits to the mother outweighs the potential risk to the fetus and child.

Cautions

–

Overdose

If you accidentally exceeding a daily dose several times may reduce blood pressure, strengthening HR, disorientation.

Treatment: symptomatic therapy.

Drug Interactions

Drug Interactions drug Eslidin^® not disclosed.

Conditions of supply of pharmacies

The drug is released under the prescription.

Conditions and terms

The drug should be stored out of reach of children at or above 25 ° C. Shelf life – 2 year. Do not use the drug after the expiry date, on the package.