Enterofuril

Active material: Nifuroksazid
When ATH: A07AX03
CCF: Intestinal antiseptics. Antidiarrheal medication
ICD-10 codes (testimony): A09
When CSF: 06.20.02
Manufacturer: BOSNALIJEK d.d. (Bosnia and Herzegovina)

PHARMACEUTICAL FORM, COMPOSITION AND PACKAGING

Capsules hard gelatin, size №0, yellow color, opaque; содержимое капсул – желтый порошок или порошок с включениями в виде небольших кусочков спрессованной массы или спрессованный порошок, which crumbles under slight pressure.

Excipients: sucrose, corn starch, cellulose powder, magnesium stearate.

Ingredients of the capsule shell: titanium dioxide C.I. 77891 (E171), quinoline yellow C.I. 47005 (E104), orange yellow C.I. 15987 (E110), painful C.I. 14720 (E122), Kosin red C.I. 16255 (E124), gelatin.

10 PC. – блистеры (3) – пачки картонные.

Capsules hard gelatin, size №0, yellow color, opaque; содержимое капсул – желтый порошок или порошок с включениями в виде небольших кусочков спрессованной массы или спрессованный порошок, which crumbles under slight pressure.

Excipients: sucrose, corn starch, cellulose powder, magnesium stearate.

Ingredients of the capsule shell: titanium dioxide C.I. 77891 (E171), quinoline yellow C.I. 47005 (E104), painful C.I. 14720 (E122), Kosin red C.I. 16255 (E124), gelatin.

8 PC. – блистеры (2) – пачки картонные.
8 PC. – блистеры (4) – пачки картонные.

Oral suspension thick, yellow color, with the smell of banana.

Excipients: sucrose, Sodium hydroxide, metilparagidroksiʙenzoat, ethanol 96%, karʙomer, lemon acid, Banana flavor, water distillirovannaya.

90 мл – флаконы темного стекла объемом 100 ml (1) в комплекте с мерной ложечкой – пачки картонные.

Pharmacological action

Antimicrobial wide spectrum of action for the treatment of gastrointestinal infections, the 5-nitrofuran. Expected, that antimicrobial and antiparasitic effect is due to the presence in the nifuroxazide NO₂-groups, which acts on the cage pathogen.

It is active against Gram-positive microbein: Staphylococcus pyogenes, Streptococcus pyogenes, Clostridium spp.; Gram-negative enterobacteria: Escherichia coli, Salmonella spp., Shigella spp., Klebsiella spp., Enterobacter spp., Vibrio cholerae, Yersinia spp., Citrobacter spp., Campylobacter spp., Edwarsiella spp.

No effect on saprophytic flora, It does not violate the balance of normal intestinal flora.

Pharmacokinetics

After taking the drug inside nifuroxazide virtually not absorbed from the gastrointestinal tract, showing their antibacterial activity only in the intestinal lumen. Fully excreted in the feces. The elimination rate depends on both the dose, and on gastrointestinal motility.

Testimony

- Acute and chronic diarrhea of ​​infectious origin (without evidence of helminthic invasion).

Dosage regimen

Adults and children over 7 years the drug is prescribed for 200 mg 4 times / day, суточная доза – 800 mg; Children from 2 to 7 years

Children under the age of 2 years drug administered only in the form of suspensions. To use the dispensing scoop. To children aged 7 months before 2 years The recommended dose is 100 mg (2.5 ml or 1/2 measuring spoon) 4 times / day, children aged 1 to 6 months – 100 mg (2.5 ml or 1/2 measuring spoon) 2-3 times / day. Before applying the suspension is necessary to mix well.

Duration of therapy should not exceed 7 days.

Side effect

Maybe: allergic reactions.

Contraindications

- Up to 1 of the month, preterm infants;

- Hypersensitivity to derivatives of nitrofuran.

Pregnancy and lactation

Can be used during pregnancy and lactation on the testimony.

Cautions

In the treatment of diarrhea while using Enterofuril should be rehydration therapy (in / or oral) in accordance with the condition of the patient and the degree of dehydration.

Against the background of Enterofuril forbidden to drink alcohol.

Overdose

No specific symptoms of overdose.

Treatment: if necessary, symptomatic therapy.

Drug Interactions

To date, drug interactions of the drug is not described Enterofuril.

Conditions of supply of pharmacies

The drug is resolved to application as an agent Valium holidays.

Conditions and terms

The drug should be stored out of reach of children at or above 30 ° C. The suspension does not freeze. Срок годности для капсул – 5 years, для суспензии для приема внутрь – 3 year.