Nifuroksazid

When ATH:
A07AX03

Pharmacological action

The antimicrobial agent broad spectrum for the treatment of gastrointestinal infections (intestinal antiseptic), nitrofuran derivative. In high doses has bactericidal action, smaller – bacteriostatic.

Active against gram-positive bacteria: Staphylococcus spp., Streptococcus spp.; Gram negative bacteria: Salmonella spp., Shigella spp., Proteus spp.

Pharmacokinetics

Almost not absorbed from the gastrointestinal tract. It acts in the lumen of the intestine.

Testimony

Acute diarrhea of ​​bacterial origin (in the absence of suspicion of infestation).

Dosage regimen

Adults – by 200 mg 4 times / day. Children aged 1 months before 2.5 years – by 100 mg 2-3 times / day; senior 2.5 years – by 200 mg 3 times / day. The duration of treatment – no more 7 days.

Side effect

Maybe: allergic reactions.

Contraindications

Hypersensitivity to the derivatives nitrofuran.

Do not use in newborns (Age to 1 of the month) and premature babies.

Pregnancy and lactation

Perhaps nifuroxazide use during pregnancy and lactation (breast-feeding) on indications.

Cautions

Application nifuroxazide not preclude the need for rehydration therapy if, if there are symptoms of dehydration.

Before use in children older 1 months should be excluded a congenital enzyme deficiency, cleaving sucrose.

Drug Interactions

Simultaneous reception of ethanol can cause symptoms of hypersensitivity.