DEFISLЁZ

Active material: Gipromelloza
When ATH: S01KA02
CCF: The preparation for moisturizing and protecting the cornea
ICD-10 codes (testimony): H02.1, H02.2, H04.1, H11.1, H16.0, H16.2, H18.1, H19.3, H53.1, M35.0, T26, Z01.0
At KFU: 26.12
Manufacturer: Synthesis of (Russia)

Pharmaceutical form, composition and packaging

◊ Eye drops a transparent or slightly opalescent, colorless or slightly colored liquid.

Excipients: benzalkonium chloride (100 ug / ml), sodium chloride (2 mg / ml), disodium эdetat (1 mg / ml), sodium dihydrogen phosphate dihydrate (3.5 mg / ml), sodium phosphate dibasic 12 water (24 mg / ml), water d / and.

10 ml – dropper bottle plastic (1) – packs cardboard.

Pharmacological action

Protector of the corneal epithelium. It has moisturizing and protective action with respect to the cornea at a reduced secretion of tear fluid. With its high viscosity, increases the contact time of the solution with the cornea. The refractive index of the solution is similar to a natural tears.

Restores, stabilizes and reproduces the optical characteristics of the tear film.

Subjective and objective improvement (reduction in congestion, epithelialization of lesions) usually occurs within 3-5 days, marked improvement or complete recovery – during 2-3 weeks.

Pharmacokinetics

The data on the pharmacokinetics Defislёz^® not provided.

Testimony

- Erosion and trophic ulcers of the cornea;

- Microtrauma corneal epithelium;

- Bullous corneal degenerative changes;

- Keratopathy;

- Ectropion;

- Lagophthalmos;

- Deformation of the Century;

- State after blepharoplasty;

- State after thermal and chemical burns of the cornea and conjunctiva;

- State after keratoplasty, keratoektomii;

- Replacement therapy at a reduced secretion of tear fluid;

- Dry eye syndrome (Sjogren syndrome), xerosis, Hyperkeratoses (in a combination therapy);

- Increased sensitivity of the eyes;

- At the end of the diagnostic procedures: Gonioscopy, electroretinography, electrooculography, ehobiometricheskoe study eyeball.

Dosage regimen

The drug should be instilled at 1-2 drops into the conjunctival sac 4-8 time / day. If necessary, can be administered 1-2 drops each hour. A course of treatment – 2-3 of the week.

Side effect

Local reactions: sense of bonding century (because of the high viscosity of the solution), allergic reactions.

Contraindications

- Hypersensitivity to the drug.

It is not recommended to use the drug in the acute phase of burn (until the complete removal of toxic substances).

Pregnancy and lactation

Data about the possibility and the safe use of the drug during pregnancy and lactation is not.

Cautions

We do not recommend wearing soft contact lenses during treatment. When wearing hard (Hardwood) contact lenses prior to instillation of the drug should be removed and re-installed on or after, than 20-30 minutes after treatment.

We do not recommend prolonged use of the drug Defislёz^®.

Effects on ability to drive vehicles and management mechanisms

Immediately after instillation possible blurred vision, which could entail difficulties in the management of a vehicle or operating machinery. Therefore, start performance of work, requiring visual acuity, be no earlier than, than later 15 min after instillation.

Overdose

When applying eye drops Defislёz^® overdose is unlikely.

Drug Interactions

The drug Defislёz^® pharmaceutically incompatible with eye drops, containing metal salts.

Conditions of supply of pharmacies

The drug is resolved to application as an agent Valium holidays.

Conditions and terms

The drug should be stored in the dark, inaccessible to children at temperature not exceeding 25 ° C; Do not freeze. Shelf life – 2 year.