Xloropiramin

When ATH:
R06AC03

Characteristic.

Ethylenediamine derivative.

Pharmacological action.
Antiallergic, antihistamine, holinoliticheskoe, sedation, snotvornoe, antispasmodic.

Application.

Allergic diseases (hives, rhinitis, conjunctivitis, pollen disease, angioedema, serum sickness), medication allergy, skin diseases (eczema, contact dermatitis, neurodermatitis, itching, toksikodermiya), the initial stages of asthma lung flow (in the complex therapy), acute respiratory infections and intestinal infections in children (in combination with antipyretics).

Contraindications.

Hypersensitivity, incl. other derivative ethylenediamine, zakrыtougolynaya glaucoma, prostate adenoma with severe urodynamics, pregnancy, lactation, Early infancy (to 1 Months).

Restrictions apply.

Aggravation of erosive and ulcerative gastrointestinal diseases, urinary retention.

Pregnancy and breast-feeding.

Contraindicated. At the time of treatment should stop breastfeeding.

Side effects.

From the nervous system and sensory organs: slackness, weakness, slowing of psychomotor reactions, drowsiness, dizziness, dystaxia.

From the digestive tract: dry mouth, nausea, gastrointestinal disorders; rarely - gastralgia.

Cooperation.

Funds, basified urine, increase, and acidifying - weaken the therapeutic and side effects. It increases the risk of seizures in the background analeptikov. It enhances the effect of narcotic analgesics, general and local anesthetics, hypnotics and sedatives, ethyl alcohol. Tricyclic antidepressants contribute to the manifestation of m-anticholinergic effects, and inhibitory action on the central nervous system. Barbiturates may accelerate the metabolism and reduce the effects of. Deprimiruyuschee effect on the central nervous system and reduced caffeine fenaminom, amplified - clonidine.

Overdose.

Symptoms: adult - confusion, depression, impairment of consciousness up to coma, possible agitation, convulsions, seldom - flushing, hyperthermia. The children - a mydriasis, hyperemia and hyperthermia, anxiety, excitation, hallucinations, ataxia, athetosis, convulsions, collapse, coma.

Treatment: gastric lavage, appointment of activated carbon, laxatives, maintaining activity of the heart and respiratory system, if necessary - anticonvulsant therapy, IVL.

Dosing and Administration.

Inside, while eating, / m and I /. Adult: by 25 mg 3-4 times a day (to 150 mg / day); / m, I / - 1-2ml 2% solution. Children: 23 times per day, 1-12 Months for 6,25 mg, 1-6 Years 8,33 mg, 7-14 Years 12,5 mg.

Precautions.

In acute allergic and anaphylactic reactions, treatment is initiated with on / in the, then move on to the / m. When applied in children requires strict medical supervision (possible manifestations of hypersensitivity). In the initial period of therapy is prohibited driving vehicles and engage in activities, requiring quick mental and motor reaction. There should be no alcohol consumption during treatment.

Cooperation