Fatty degeneration of the liver – treatment of disease. Symptoms and prevention of the disease the fatty degeneration of the liver

Fatty degeneration of the liver – What is this disease? Fatty degeneration of the liver (stetogepatoz) is a chronic liver disease, which is most often the fatty hepatosis views vstrechaemym, characterized by fatty (the accumulation of lipids) hepatic tissue.

Statistically, about 25% the population of developed countries suffer this pathology. Most often the fatty liver degeneration observed in persons with obesity and diabetes 2 type.

Fatty degeneration of the liver – The cause of the

Reasons for the development of fatty degeneration of the liver can be various metabolic disorders (metabolic factors), gepatotoksicskie substances, some diseases and surgery on organs of the gastrointestinal tract, hereditary factors, etc.. Among the Etiologic factors include steatogepatoza:

• diabetes, hypertriglyceridemia;
• poor nutrition (starvation, overeating, large consumption of fatty and carbohydrate food, protein deficiency in the diet), obesity;
• excessive alcohol consumption (more than 30 ml per day);
• genetic predisposition;
• increasing the level of GH leadership (When endocrine pathologies, traumatic brain injuries, pituitary dysfunctions, etc.);
• chronic diseases of DIGESTIVE TRACT, violating suction;
• acceptance of certain medicines, their intoxication (certain antibiotics, glukokorticosteroida, non-steroidal anti-inflammatory drugs, cytostatics);
• heavy chronic diseases (heart failure, respiratory insufficiency, malignant neoplasms);
• myxedema, Cushing's syndrome;
• surgery (gastroplastika, extensive resection of the small bowel, Ilio-toshhekishechnyj anastomosis).

Factors, a debilitating impact on prognosis, are female gender, Age more 45 years, diabetes 2 type, otjagoshhjonnyj family history on this disease, significant obesity.

Fatty degeneration of the liver – Symptoms of fatty degeneration of the liver

This disease for a long time may not manifest itself clinically. With the progression of Dystrophic processes in the liver, the following symptoms may appear:

• asthenic syndrome (generalized weakness, fatigue);
• discomfort, the severity of the, and then the pain in the right hypochondrium;
• decreased appetite, nausea, possible vomiting bile with impurities;
• zheltushnost' skin and mucous membranes;
• itching;
• signs of decreasing immunity (frequent ORZ);
• in severe cases, signs of hepatic cell failure.

Fatty degeneration of the liver – Diagnostics

In the diagnosis of fatty liver degeneration, In addition to the clinical picture described earlier, take into account the results of such laboratory and instrumental examination methods:

• General clinical blood analysis (perhaps identifying anemia, Leukocytosis, increased erythrocyte sedimentation rate);
• biochemical blood analysis (increasing the level of hepatic transaminases, GGT, direct bilirubin, cholesterol);
• ultrasound of the liver (its increase and structure change);
• CT and MRI of the liver;
• elastography of the liver (for the exception of cirrhosis and fibrosis of the liver);
• roasted biopsy (the most informative research method).

Fatty degeneration of the liver – Classification

On the jetiologicheskomu basis of the fatty degeneration of the liver is divided into primary and secondary (occurs in the face of other diseases, as diabetes mellitus), as well as alcohol and nealkogol'nuju.

Depending on the nature of the spread of the disease process in liver tissue and diffuse nodulous distinguish the fatty degeneration of the liver.

By morphology (When microscopic biopsy) allocate melkokapel'nuju and krupnokapel'nuju fatty degeneration (infiltration) liver.

Fatty degeneration of the liver – Actions of the patient

Upon detection of any symptoms, described in the corresponding section, You should contact a specialist (physician-gastroenterologist) for examination and early detection of Pathology.

Treatment of fatty degeneration of the liver

In the initial stages of the development of fatty degeneration of the liver is reversible. When the secondary steatogepatoze must first treatment of the underlying disease, against which developed this pathology. When the alcoholic origin diseases should abandon alcohol. All patients to diet with restriction of the consumption of animal fats and carbohydrates, Obesity-weight loss. Medical therapy is the use of gepatoprotektornyh funds, lipotropic drugs, Ursodeoxycholic acid, vitamins c and e, and in the development of liver failure-medical therapy of the complications.

Fatty degeneration of the liver – Complications

Fatty degeneration of the liver may be complicated joining of the inflammatory process (steatohepatitis), fibrosis or cirrhosis of the liver, Cholestasis (stagnation of bile), as well as the development of hepatic failure.

Prevention of fatty degeneration of the liver

Prevention of this disease is to refuse from alcohol, conduct healthy lifestyle, normalization of body weight, treatment of diseases, capable of provoking the development of fatty liver (endocrine pathology, chronic diseases of gastrointestinal tract, etc.).