Lagochilus inebrians – Lagohilus intoxicating – Lagochilus inebriating
Long-term shrub height of 45-50 cm, families gubotsvetnыh (Labiateae). Lagochilus inebrians distributed in Uzbekistan, Tajikistan and in the Altai. For therapeutic purposes, using the aerial part of the plant.
Zaytsegub intoxicating – Chemical composition
The herb contains tannins zaytseguba, sugar, essential oil, lagokhilin (chetyrehatomny alcohol), ascorbic acid and carotene.
Lagochilus inebrians – Pharmacological properties
A large amount of experimental studies, conducted with pharmaceutical and neogalenic forms lagochilus inebrians, revealed a high hemostatic activity plant. Preparations lagohilusa increase as the ability of the blood coagulation by activation of plasma coagulation factors and cell, and due to the depression of anticoagulation. The most active have an infusion broth and plants.
Infusion and extract lagohilusa, as well as the drug "Lagohilen» in vitro when administered intravenously to animals inhibit the fibrinolytic activity of the blood plasma by aktyvatsii inhibitors and inhibit the activity of fibrinolysis proactivator.
In addition to the hemostatic and antifibrinolytic activity, in preparations lagohilusa were found and other properties. For Example, aqueous extracts lagohilusa Sedative, hypotensive and allergen activity, and also stimulate contractility of uterine smooth muscle, contractile and motor function of the stomach and intestines. Besides, lagohilusa experimental drugs inhibit intestinal spasm karboholinovy, prevent the development or facilitate for shock.
In tests on warm-blooded animals have shown, that daily subcutaneous infusion lagohilusa after a single x-ray exposure to sublethal doses promotes more rapid recovery of the body's vital functions and performance. Besides, lagohilusa drugs have sedating effects and enhance inhibitory processes in the cerebral cortex, and also contribute to the removal of animals from the state of experimental neurosis, have a pronounced anticonvulsant effect after the administration of stimulants, like strychnine, caffeine, etc.. In experiments on different animal species has been found, that under the influence of drugs lagohilusa a noticeable decrease in the permeability of vascular wall of arterioles and capillaries.
Lagochilus inebrians – Use in medicine
Preparations lagohilusa used as an effective hemostatic agent in the lung, nasal, hemorrhoidal, tubal, traumatic bleeding, and to prevent excessive bleeding during surgery.
In the appointment of an alcohol tincture lagohilusa children, patients with hemophilia A, It marked the acceleration of blood clotting and a significant increase of antihemophilic globulin. Infusion and dry extract lagohilusa also effective in hemophilia. Clinical observations have shown, that the treatment of patients with hemophilia drugs lagohilusa improving their overall, increased periods of remission, shortened bleeding time, and its intensity is weakened, reduced time resorption of hematomas and hemarthrosis, decreases pain of the affected organs. When applied topically, the infusion and tincture lagohilusa also have a hemostatic effect.
Besides, lagohilusa herbal medicines used in functional diseases of the central nervous system, hypertensive disease, allergic skin diseases, haemorrhagic diathesis, glaucoma, gastric ulcer and duodenal ulcer.
When using drugs lagohilusa side effects not found. With increased heart rate should abstain reduce the dose.
Lagochilus inebrians – Formulations, Dosing and Administration
Infusion lagohilusa: 10 g leaves of the plant (1 tablespoon) placed in an enamel bowl, Pour 200 ml (1 glass) hot boiled water, close lid, heating it in a boiling water bath for 15 m, then cooled to room temperature 45 m, filter, the remaining raw materials squeeze. The volume of the resulting infusion was adjusted with boiled water to 200 ml. Accepted into 1-2 tablespoons 3-5 times a day as a styptic.
When hemorrhagic diathesis is usually prescribed 1 / 2-1 / 3 cup of infusion 3-4 times a day. Besides, lagohilusa infusion used topically; they moistened gauze, which is applied to bleeding tissue sections for 3-5 minutes.
Tincture lagohilusa - 70 % alcoholic extract from the leaves of plants. Indications for the same, as for the infusion lagohilusa. Apply 1-2 teaspoons of tincture on 1/2 glasses of water to receive 3-5 times a day.
Tablets lagohilusa, containing 0,2 g of dry extract lagohilusa, used as a styptic in uterine, hemorrhoidal, nosebleeds, etc.. to prevent excessive bleeding during surgery. Assign 1 tablet 3-4 times a day. Tablets lagohilusa used as a sedative and in functional disorders of the CNS.
