TSITOVIR-3
Active material: Vitamin C, Bendazol, timogen
When ATH: L03AX
CCF: Immunostimulatory drug
ICD-10 codes (testimony): J06.9, J10
When CSF: 14.01.06
Manufacturer: MBNPK TSITOMED Company (Russia)
Pharmaceutical form, composition and packaging
◊ Capsules hard gelatin, with white body and orange cap.
| 1 ml | |
| timogen (α-glutamyl-tryptophan, sodium salt) | 500 g |
| bendazol | 20 mg |
| vitamin C | 50 mg |
Excipients: lactose, calcium stearate.
12 PC. – packings Valium planimetric (1) – packs cardboard.
12 PC. – plastic jars (1) – packs cardboard.
Syrup for children yellow or light yellow.
| 1 ml | |
| timogen (α-glutamyl-tryptophan, sodium salt) | 150 g |
| bendazol | 1.25 mg |
| vitamin C | 12 mg |
Excipients: sucrose, Purified water.
50 ml – vials of dark glass (1) complete with a dosing spoon – packs cardboard.
Pharmacological action
Immunomodulatory drugs, affect the reaction cell, humoral immunity and nonspecific resistance of the organism. It has interferonogenic action.
Part of the preparation bendazol induces endogenous interferon. Enzymes, interferon induced in cells of various organs, inhibit viral replication. Besides, activating the immune cells, drug helps normalize immune status.
Timogen effect on T-cell immunity.
Ascorbic acid activates humoral immunity, normalizes capillary permeability, thereby suppressing inflammation.
Pharmacokinetics
Absorption
After ingestion completely absorbed from the gastrointestinal tract. Bioavailability bendazol – about 80%, timogena – no more 15% and ascorbic acid – 90%.
Metabolism
Timogen under the influence of peptidases splits into L- glyutaminovuyu kislotu and L-tryptophan, which are used by the body in the synthesis of proteins.
Deduction
Metabolites of ascorbic acid and excreted in the urine bendazol. T1/2 component does not exceed 3 no.
Testimony
- Prevention and symptomatic treatment of early stages of influenza and other acute respiratory viral infections.
Dosage regimen
The drug is taken orally for 30 minutes before eating.
With the aim of prevention and treatment of adults and children over 6 years appoint 1 caps. 3 times / day for 4 days.
Children aged 1 Year to 3 years appoint 2 ml syrup 3 times / day for 4 days; children aged 3 to 6 years – by 4 ml 3 times / day for 4 days; children aged 6 to 10 years – by 8 ml 3 times / day for 4 days; children over the age of 10 years – by 12 ml 3 times / day for 4 days.
FROM prophylactically a second course of treatment can be carried out through 3-4 of the week.
Side effect
Cardio-vascular system: short-term reduction in blood pressure (in patients with dystonia neurocirculatory).
Other: allergic reactions.
Contraindications
- Diabetes (syrup);
- Children up to age 6 years (Capsule);
- Pregnancy (Capsule);
- Lactation (Capsule);
- Hypersensitivity to the drug.
Pregnancy and lactation
The drug is contraindicated during pregnancy and lactation.
Cautions
With prolonged use of the syrup is necessary periodic monitoring of kidney function and blood glucose levels.
At the recommended doses, the drug Tsitovir®-3 compatible with all means, applied for the symptomatic treatment of influenza and other acute respiratory viral infections.
Overdose
Data on drug overdose Tsitovir®-3 no.
Drug Interactions
Drug Interactions drug Tsitovir®-3 not disclosed.
Conditions of supply of pharmacies
The capsules are approved for use as a means of non-prescription.
Syrup by prescription.
Conditions and terms
List B. The drug should be stored in a dry, protected from light, inaccessible to children at temperature not exceeding 25 ° C. Shelf life of capsules – 3 year, syrup - 2 year.
