Nevrilemmoma - neuromas – Schwannomas

Nevrilemmoma (neurinoma, schwannomas) - A benign tumor, Related neyrolemmoy nerve fibers. Develops along the nerve trunks, soft tissue, in including in the neck during the cranial nerves, and less in the internal organs.

The same type detected punctate tumor cells elongate, fusiform round, oval and rod-intensive staining nuclei with dense granular structure of chromatin. The nucleoli are absent. Basophilic cytoplasm, dramatically extended by poles of the cell, sometimes with unclear borders. The end portions of the cytoplasm gradually become thinner and can be cleaved, forming processes as threads. Cells are located nevrilemmomy intertwining strands or bundles. Sometimes the cells form a structure of beams in the form of turbulence, parallel rows or palisade structures, as well as on the background mesh weave slizevidnogo amorphous substance.

There are also the so-called calf Verokai, verification which cytological preparations more difficult, than histological sections. They are winding ribbon-like formation, consisting of two, located palisade, parallel rows of cells, between which the homogeneous ground substance, painted in light blue tones.

Taurus Verokai characteristic of nevrilemmomy, but sometimes can also be found in other types of tumors - LM, fibroma. When stained by Van Gieson calf Verokai, belonging nevrilemmome, painted in yellow color, and fibroma - red.

Morphologically there are two types nevrilemmomy:

• type A (nevrilemmoma Verokai);
• тип B по Антони.

In type A in the preparation of the same type on a background of spindle-shaped cells with dramatically elongated at the poles of the nucleus cytoplasm detected calf Verokai. In type B are absent. In cytologic specimen dominated by larger, several polymorphous cells predominantly elongated shape with long cytoplasmic processes, number may be different. There are also cells mnogootrostchatye.

Scion have different shapes and depart in different directions. Long spines gradually thinning. The cell nuclei are small nevrilemmomy, most of rod-shaped, hyperchromatic. In the cytoplasm of some cells around the nucleus has a pinkish grain. Between the cells revealed mucoid substance. Scraps of capillaries may occur, ksantomatoznye cells.

Malignant nevrilemmoma – Malignant schwannoma – Neurogenic sarcoma)

Rarely, usually in young men. Microscopically it is characterized by mild polymorphic atypical cells with large hyperchromatic nuclei oval, elongated or irregularly rounded shape, often with indistinct edges. There are cells in mitosis. Cytoplasm of elongated pole, Process, often fissile ends. Cells are arranged randomly or in the form of interwoven beams, palisadov, vorticity. There are also foam cells, scraps of capillaries, multicore symplast and stellate retikuloendoteliotsity.